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Sir Douglass Matthew Turnbull FRS FMedSci is Professor of Neurology at Newcastle University , an Honorary Consultant Neurologist at Newcastle upon Tyne Hospitals NHS Foundation Trust [1] Wellcome Trust Centre for Mitochondrial Research .[2] [3] [4] [5]
Education [ edit ]
Turnbull was educated at Newcastle University , where he was awarded a Bachelor of Medicine, Bachelor of Surgery and qualifying as a junior doctor .[when? [2] PhD for research investigating Mitochondrial cytopathies.[6]
Research [ edit ]
Turnbull's research investigates techniques for improving the lives of patients with mitochondrial disease .[7] [update] [2] [8] peer reviewed scientific journals such as Nature [3] Nature Genetics [9] [10] Nature Reviews Genetics ,[11] American Journal of Human Genetics ,[12] Journal of Clinical Investigation [13]
His research has been funded by the Wellcome Trust , the Biotechnology and Biological Sciences Research Council (BBSRC) and the Medical Research Council (MRC) .[14]
Awards and honours [ edit ]
Turnbull delivered the Goulstonian Lectures in 1992 and was awarded the Jean Hunter Prize in 2003, both by the Royal College of Physicians .[2] Fellow of the Academy of Medical Sciences in 2004.[15]
Turnbull was knighted in the 2016 Birthday Honours .[16] IVF technique which prevents disabling genetic disorders from being passed on to future generations".[17] mitochondrial donation , also known as "three-person babies".[18] [19]
Turnbull was awarded the Buchanan Medal for outstanding contributions to biomedicine particularly in relation to mitochondrial disease, including the development of a method to prevent their transmission.[20]
References [ edit ]
^ a b Craven, Lyndsey; Tuppen, Helen A.; Greggains, Gareth D.; Harbottle, Stephen J.; Murphy, Julie L.; Cree, Lynsey M.; Murdoch, Alison P.; Chinnery, Patrick F.; Taylor, Robert W.; Lightowlers, Robert N.; Herbert, Mary; Turnbull, Douglass M. (2010). "Pronuclear transfer in human embryos to prevent transmission of mitochondrial DNA disease" . Nature . 465 (7294): 82–85. Bibcode :2010Natur.465...82C . doi :10.1038/nature08958 . PMC 2875160 PMID 20393463 .
^ Healing broken batteries: The Wellcome Trust Centre for Mitochondrial Research on YouTube , Wellcome Trust , London
^ Graeme Whitfield (2015). "Newcastle University medical pioneer Doug Turnbull discusses his game-changing research" . thejournal.co.uk . Newcastle: The Journal . Archived from the original on 2020-08-18. Retrieved 2016-06-16 .
^ Turnbull, Douglass Matthew (1983). Mitochondrial cytopathies: clinical and experimental studies OCLC 11274373 .
^ Lightowlers, Robert N.; Chinnery, Patrick F.; Turnbull, Douglass M.; Howell, Neil (1997). "Mammalian mitochondrial genetics: heredity, heteroplasmy and disease". Trends in Genetics . 13 11 ): 450–455. doi :10.1016/S0168-9525(97 )01266-3 . PMID 9385842 .
^ Douglass Turnbull's publications indexed by the Scopus bibliographic database. (subscription required)
^ Turnbull, Douglass M.; Andrews, Richard M.; Kubacka, Iwona; Chinnery, Patrick F.; Lightowlers, Robert N.; Howell, Neil (1999). "Reanalysis and revision of the Cambridge reference sequence for human mitochondrial DNA" . Nature Genetics . 23 2 ): 147. doi :10.1038/13779 PMID 10508508 .
^ Bender, Andreas; Krishnan, Kim J; Morris, Christopher M; Taylor, Geoffrey A; Reeve, Amy K; Perry, Robert H; Jaros, Evelyn; Hersheson, Joshua S; Betts, Joanne; Klopstock, Thomas; Taylor, Robert W; Turnbull, Douglass M (2006). "High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease". Nature Genetics . 38 5 ): 515–517. doi :10.1038/ng1769 . PMID 16604074 . S2CID 13956928 .
^ Taylor, Robert W.; Turnbull, Doug M. (2005). "Mitochondrial DNA mutations in human disease" . Nature Reviews Genetics . 6 5 ): 389–402. doi :10.1038/nrg1606 . PMC 1762815 PMID 15861210 .
^ Herrnstadt, Corinna; Elson, Joanna L.; Fahy, Eoin; Preston, Gwen; Turnbull, Douglass M.; Anderson, Christen; Ghosh, Soumitra S.; Olefsky, Jerrold M.; Beal, M. Flint; Davis, Robert E.; Howell, Neil (2002). "Reduced-Median-Network Analysis of Complete Mitochondrial DNA Coding-Region Sequences for the Major African, Asian, and European Haplogroups" . The American Journal of Human Genetics . 70 5 ): 1152–1171. doi :10.1086/339933 . PMC 447592 PMID 11938495 .
^ Taylor, Robert W.; Barron, Martin J.; Borthwick, Gillian M.; Gospel, Amy; Chinnery, Patrick F.; Samuels, David C.; Taylor, Geoffrey A.; Plusa, Stefan M.; Needham, Stephanie J.; Greaves, Laura C.; Kirkwood, Thomas B.L.; Turnbull, Douglass M. (2003). "Mitochondrial DNA mutations in human colonic crypt stem cells" . Journal of Clinical Investigation . 112 (9 ): 1351–1360. doi :10.1172/JCI19435 . PMC 228466 PMID 14597761 .
^ "UK Government grants awarded to Doug Turnbull" . rcuk.ac.uk . Swindon: Research Councils UK . Archived from the original on 2016-06-16.
^ "Professor Doug Turnbull FMedSci" . acmedsci.ac.uk . London: Academy of Medical Sciences . Archived from the original on 2016-06-16.
^ "No. 61608" . The London Gazette
^ Anon (2016). "Birthday honours: Mitochondrial disease doctor recognised" . bbc.co.uk . London: BBC News .
^ Mark Henderson (2015). "Three-person embryos: how the mitochondrial donation battle was won. Prof Doug Turnbull successfully communicated difficult and controversial research with scientific accuracy, but in simple terms" . The Guardian the original on 2016-02-05.
^ James Gallagher (2015). "Three-person babies - not three-parent babies" . bbc.co.uk . London: BBC News . Archived from the original on 2016-03-02.
^ "Buchanan Medallist 2020" . Royal Society. Archived from the original on 23 October 2019. Retrieved 18 August 2020 .
R e t r i e v e d f r o m " https://en.wikipedia.org/w/index.php?title=Douglass_Turnbull&oldid=1206519039 " C a t e g o r i e s : ● B r i t i s h n e u r o l o g i s t s ● L i v i n g p e o p l e ● F e l l o w s o f t h e A c a d e m y o f M e d i c a l S c i e n c e s ( U n i t e d K i n g d o m ) ● K n i g h t s B a c h e l o r ● N I H R S e n i o r I n v e s t i g a t o r s H i d d e n c a t e g o r i e s : ● P a g e s c o n t a i n i n g l i n k s t o s u b s c r i p t i o n - o n l y c o n t e n t ● P a g e s c o n t a i n i n g L o n d o n G a z e t t e t e m p l a t e w i t h p a r a m e t e r s u p p s e t t o y ● A r t i c l e s w i t h h C a r d s ● A l l a r t i c l e s w i t h v a g u e o r a m b i g u o u s t i m e ● V a g u e o r a m b i g u o u s t i m e f r o m J u n e 2 0 1 6 ● A r t i c l e s c o n t a i n i n g p o t e n t i a l l y d a t e d s t a t e m e n t s f r o m 2 0 1 6 ● A l l a r t i c l e s c o n t a i n i n g p o t e n t i a l l y d a t e d s t a t e m e n t s ● A r t i c l e s w i t h I S N I i d e n t i f i e r s ● A r t i c l e s w i t h G o o g l e S c h o l a r i d e n t i f i e r s ● A r t i c l e s w i t h O R C I D i d e n t i f i e r s ● Y e a r o f b i r t h m i s s i n g ( l i v i n g p e o p l e )
● T h i s p a g e w a s l a s t e d i t e d o n 1 2 F e b r u a r y 2 0 2 4 , a t 1 0 : 4 3 ( U T C ) . ● T e x t i s a v a i l a b l e u n d e r t h e C r e a t i v e C o m m o n s A t t r i b u t i o n - S h a r e A l i k e L i c e n s e 4 . 0 ;
a d d i t i o n a l t e r m s m a y a p p l y . B y u s i n g t h i s s i t e , y o u a g r e e t o t h e T e r m s o f U s e a n d P r i v a c y P o l i c y . W i k i p e d i a ® i s a r e g i s t e r e d t r a d e m a r k o f t h e W i k i m e d i a F o u n d a t i o n , I n c . , a n o n - p r o f i t o r g a n i z a t i o n . ● P r i v a c y p o l i c y ● A b o u t W i k i p e d i a ● D i s c l a i m e r s ● C o n t a c t W i k i p e d i a ● C o d e o f C o n d u c t ● D e v e l o p e r s ● S t a t i s t i c s ● C o o k i e s t a t e m e n t ● M o b i l e v i e w
