Ectopic testis is used to describe the testis leaving the inguinal canal and entering a site other than the scrotum. Usually, it results from obstruction of the scrotal entrance or from overdevelopment and lengthening of a segment of the gubernaculum.[1]
The positions of the ectopic testis may be: in the lower part of the abdomen, front of thigh, femoral canal, skin of penis or behind the scrotum. The testis is usually developed, and accompanied by an indirect inguinal hernia. It may be divorced from the epididymis which may lie in the scrotum.[2][3]
The ectopic testis can be in the perineal region, the opposite side of the scrotum, the suprapubic region, the femoral region, or in the superficial inguinal pouch.[1]
The ectopic testis is initially normal, but if it is ignored after childhood, it may become small and soft, with spermatogenesis arresting and interstitial cell proliferation occurring.[4]
There is debate regarding the etiopathogenesis of ectopic testis.[6] It could be caused by local mechanical barriers obstructing the normal descent, aberrant gubernacular stabilization as a result of an anomaly at its distal end, or aberrant interaction between androgen and calcitonin gene-related peptide (CGRP).[7][8]
Diagnosis can be made based on the presence of an empty scrotum and swelling in the perineal area. Diagnosis can also be aided by palpation of the testis. Imaging methods like tomography and ultrasound might be necessary on occasion.[9]
^Stevenson, Roger; Hall, Judith (2006). Human malformations and related anomalies. Oxford New York: Oxford University Press. p. 1272. ISBN0-19-516568-3.
^Middleton, George W.; Beamon, Charles R.; Gillenwater, Jay Y. (1976). "Two Rare Cases of Ectopic Testis". Journal of Urology. 115 (4). Ovid Technologies (Wolters Kluwer Health): 455–458. doi:10.1016/s0022-5347(17)59241-1. ISSN0022-5347. PMID4633.
^Ramareddy, Raghu S.; Alladi, Anand; Siddappa, O.S. (2013). "Ectopic testis in children: Experience with seven cases". Journal of Pediatric Surgery. 48 (3). Elsevier BV: 538–541. doi:10.1016/j.jpedsurg.2012.10.005. ISSN0022-3468. PMID23480908.
^HUTCHESON, JOEL C.; SNYDER, HOWARD M.; ZUÑIGA, ZACHARY V.; ZDERIC, STEPHEN A.; SCHULTZ, DELRAY J.; CANNING, DOUGLAS A.; HUFF, DALE S. (2000). "Ectopic and Undescended Testes: 2 Variants of a Single Congenital Anomaly?". Journal of Urology. 163 (3). Ovid Technologies (Wolters Kluwer Health): 961–963. doi:10.1016/s0022-5347(05)67864-0. ISSN0022-5347. PMID10688032.
