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Contents

   



(Top)
  


1 See also  




2 References  













Fletazepam






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From Wikipedia, the free encyclopedia
  

Fletazepam
Clinical data
ATC code
  • none
Identifiers

  • 7-chloro-5-(2-fluorophenyl)-1-(2,2,2-trifluoroethyl)-2,3-dihydro-1,4-benzodiazepine

CAS Number
PubChem CID
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
ECHA InfoCard100.047.309 Edit this at Wikidata
Chemical and physical data
FormulaC17H13ClF4N2
Molar mass356.75 g·mol−1
3D model (JSmol)

  • FC1=CC=CC=C1C2=NCCN(CC(F)(F)F)C3=C2C=C(Cl)C=C3

  • InChI=1S/C17H13ClF4N2/c18-11-5-6-15-13(9-11)16(12-3-1-2-4-14(12)19)23-7-8-24(15)10-17(20,21)22/h1-6,9H,7-8,10H2 checkY

  • Key:CIZCSUNUBQXVFP-UHFFFAOYSA-N checkY

  (verify)

Fletazepam[1] is a drug which is a benzodiazepine derivative. It has sedative and anxiolytic effects similar to those produced by other benzodiazepine derivatives, but is mainly notable for its strong muscle relaxant properties.[2]

Fletazepam is most closely related to other N-trifluoroethyl substituted benzodiazepines such as halazepam and quazepam.[3]

See also[edit]

References[edit]

  1. ^ DE 2106175, Steinmann, Martin, "Neue 1-Polyfluoralkylbenzodiazepine und Verfahren zu ihrer Herstellung [Novel 1-polyfluoroalkylbenzodiazepines and processes for their preparation]", published 1971-09-30, assigned to Sherico Ltd. 
  • ^ Barnett A, Goldstein J, Fiedler EP, Taber RI (November 1974). "The pharmacology of fletazepam a centrally-acting muscle relaxant". Archives Internationales de Pharmacodynamie et de Therapie. 212 (1): 164–74. PMID 4476200.
  • ^ Iorio LC, Barnett A, Billard W (July 1984). "Selective affinity of 1-N-trifluoroethyl benzodiazepines for cerebellar type 1 receptor sites". Life Sciences. 35 (1): 105–13. doi:10.1016/0024-3205(84)90157-7. PMID 6738302.
    • Stub icon

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    • Retrieved from "https://en.wikipedia.org/w/index.php?title=Fletazepam&oldid=1215443310"
    Categories: 
    ●Drugs not assigned an ATC code
     ●Benzodiazepines
     ●Chloroarenes
     ●Trifluoromethyl compounds
     ●Fluoroarenes
     ●Sedative stubs
     Hidden categories: 
    ●Articles with short description
     ●Short description matches Wikidata
     ●ECHA InfoCard ID from Wikidata
     ●Articles without EBI source
     ●Chemical pages without DrugBank identifier
     ●Drugs with no legal status
     ●Drugboxes which contain changes to watched fields
     ●All stub articles
      


    ●This page was last edited on 25 March 2024, at 04:39 (UTC).
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