Spray containing propane, butane, and ethanol, for dental applications
Freeze spray (cold sprayorvapocoolant) is a type of aerosol spray product containing a liquified gas used for rapidly cooling surfaces, in medical and industrial applications. It is usually sold in hand-held spray cans. It may consist of various substances, which produce different temperatures, depending on the application.
In medical applications, spray cans containing dimethyl ether[4] or tetrafluoroethane may also be used to freeze and destroy tissue, for removal of warts and skin tags, or other uses in cryosurgery. Liquified petroleum gas including propane and butane is sometimes used. These all may also be used as a topical anesthetic, due to the numbing effect of cold, though there is risk of frostbite.
Chloroethane may be used as a topical pain reliever, and an alternative to ice pack therapy to reduce inflammation and swelling. Since its boiling point is well above the freezing point of water, there is less risk of freezing the skin, though it can still be dangerous if misused. It may be used to treat sports injuries, where it is sometimes known as ice sprayormagic spray.[5]
Freeze sprays are also utilized in frozen section biopsies to rapidly cool or freeze small tissue samples at the microtomeorcryostat.[6]
Freeze spray has been shown useful for the field marking of animals; for example marking the tails of monkeys. Research is continuing to help control the application dosage and time to minimize permanent damage to the animals.[7]
^Shadgan B, Med S, Pakravan AH, Hoens A, Reid WD. Subcutaneous and Intramuscular Hemodynamics and Oxygenation After Cold-Spray Application as Monitored by Near-Infrared Spectroscopy. J Athl Train. 2015;50(8):800-805. doi:10.4085/1062-6050-50.6.02
