Progonadoliberin-2 is a protein that in humans is encoded by the GNRH2 gene.[1][2][3]
The protein encoded by this gene is a preproprotein that is cleaved to form a secreted 10 aa peptide hormone, QHWSHGWYPG
.[4] The secreted decapeptide regulates reproduction in females by stimulating the secretion of both luteinizing- and follicle-stimulating hormones. Three transcript variants that encode unique proproteins but the same peptide hormone have been found for this gene.[3] The peptide belongs to gonadotropin-releasing hormone family.
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