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1 See also  





2 References  





3 Further reading  














GPR4






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GPR4
Identifiers
AliasesGPR4, G protein-coupled receptor 4, GPR6C.l
External IDsOMIM: 600551; MGI: 2441992; HomoloGene: 3867; GeneCards: GPR4; OMA:GPR4 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005282

NM_175668

RefSeq (protein)

NP_005273

NP_783599

Location (UCSC)Chr 19: 45.59 – 45.6 MbChr 7: 18.95 – 18.96 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

G-protein coupled receptor 4 is a protein that in humans is encoded by the GPR4 gene.[5][6]

See also

[edit]

References

[edit]
  • ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  • ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  • ^ Mahadevan MS, Baird S, Bailly JE, Shutler GG, Sabourin LA, Tsilfidis C, Neville CE, Narang M, Korneluk RG (Apr 1996). "Isolation of a novel G protein-coupled receptor (GPR4) localized to chromosome 19q13.3". Genomics. 30 (1): 84–8. doi:10.1006/geno.1995.0013. PMID 8595909.
  • ^ "Entrez Gene: GPR4 G protein-coupled receptor 4".
  • Further reading

    [edit]
  • Heiber M, Docherty JM, Shah G, Nguyen T, Cheng R, Heng HH, Marchese A, Tsui LC, Shi X (1995). "Isolation of three novel human genes encoding G protein-coupled receptors". DNA Cell Biol. 14 (1): 25–35. doi:10.1089/dna.1995.14.25. PMID 7832990.
  • Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Lum H, Qiao J, Walter RJ, Huang F, Subbaiah PV, Kim KS, Holian O (2003). "Inflammatory stress increases receptor for lysophosphatidylcholine in human microvascular endothelial cells". Am. J. Physiol. Heart Circ. Physiol. 285 (4): H1786–9. doi:10.1152/ajpheart.00359.2003. PMID 12805023.
  • Ludwig MG, Vanek M, Guerini D, Gasser JA, Jones CE, Junker U, Hofstetter H, Wolf RM, Seuwen K (2003). "Proton-sensing G-protein-coupled receptors". Nature. 425 (6953): 93–8. Bibcode:2003Natur.425...93L. doi:10.1038/nature01905. PMID 12955148. S2CID 4395698.
  • Bektas M, Barak LS, Jolly PS, Liu H, Lynch KR, Lacana E, Suhr KB, Milstien S, Spiegel S (2003). "The G protein-coupled receptor GPR4 suppresses ERK activation in a ligand-independent manner". Biochemistry. 42 (42): 12181–91. doi:10.1021/bi035051y. PMID 14567679.
  • Sin WC, Zhang Y, Zhong W, Adhikarakunnathu S, Powers S, Hoey T, An S, Yang J (2004). "G protein-coupled receptors GPR4 and TDAG8 are oncogenic and overexpressed in human cancers". Oncogene. 23 (37): 6299–303. doi:10.1038/sj.onc.1207838. PMID 15221007. S2CID 23448180.
  • Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Kim KS, Ren J, Jiang Y, Ebrahem Q, Tipps R, Cristina K, Xiao YJ, Qiao J, Taylor KL (2005). "GPR4 plays a critical role in endothelial cell function and mediates the effects of sphingosylphosphorylcholine". FASEB J. 19 (7): 819–21. doi:10.1096/fj.04-2988fje. PMID 15857892. S2CID 23640250.
  • Qiao J, Huang F, Naikawadi RP, Kim KS, Said T, Lum H (2006). "Lysophosphatidylcholine impairs endothelial barrier function through the G protein-coupled receptor GPR4". Am. J. Physiol. Lung Cell Mol. Physiol. 291 (1): L91–101. doi:10.1152/ajplung.00508.2005. PMID 16461426. S2CID 25149978.
  • Huang F, Mehta D, Predescu S, Kim K, Lum H (2007). "A novel lysophospholipid- and pH-sensitive receptor, GPR4, in brain endothelial cells regulates monocyte transmigration". Endothelium. 14 (1): 25–34. doi:10.1080/10623320601177288. PMID 17364894.
  • Zou Y, Kim CH, Chung JH, Kim JY, Chung SW, Kim MK, Im DS, Lee J, Yu BP (2007). "Upregulation of endothelial adhesion molecules by lysophosphatidylcholine. Involvement of G protein-coupled receptor GPR4". FEBS J. 274 (10): 2573–84. doi:10.1111/j.1742-4658.2007.05792.x. PMID 17437524. S2CID 83245004.
  • Tobo M, Tomura H, Mogi C, Wang J, Liu J, Komachi M, Damirin A, Kimura T, Murata N (2007). "Previously postulated "ligand-independent" signaling of GPR4 is mediated through proton-sensing mechanisms". Cell. Signal. 19 (8): 1745–53. doi:10.1016/j.cellsig.2007.03.009. PMID 17462861.
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  • Retrieved from "https://en.wikipedia.org/w/index.php?title=GPR4&oldid=1199435652"

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    This page was last edited on 27 January 2024, at 02:03 (UTC).

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