Main menu Navigation ●Main page ●Contents ●Current events ●Random article ●About Wikipedia ●Contact us ●Donate Contribute ●Help ●Learn to edit ●Community portal ●Recent changes ●Upload file

●Create account ●Log in ●Create account ● Log in Pages for logged out editors learn more ●Contributions ●Talk

(Top) 1 References

Gabexate

●العربية ●한국어 ●Italiano ●Српски / srpski ●Srpskohrvatski / српскохрватски Edit links ●Article ●Talk ●Read ●Edit ●View history Tools Actions ●Read ●Edit ●View history General ●What links here ●Related changes ●Upload file ●Special pages ●Permanent link ●Page information ●Cite this page ●Get shortened URL ●Download QR code ●Wikidata item Print/export ●Download as PDF ●Printable version Appearance From Wikipedia, the free encyclopedia

Gabexate
Clinical data

AHFS/Drugs.com	International Drug Names
ATC code	none
Identifiers
IUPAC name ethyl 4-[6-(diaminomethylideneamino)hexanoyloxy]benzoate
CAS Number	39492-01-8^Y
PubChem CID	3447
IUPHAR/BPS	7863
ChemSpider	3329^N
UNII	4V7M9137X9
KEGG	D08004^Y
ChEMBL	ChEMBL87563^N
CompTox Dashboard (EPA)	DTXSID9048566
Chemical and physical data
Formula	C₁₆H₂₃N₃O₄
Molar mass	321.377 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES O=C(Oc1ccc(cc1)C(=O)OCC)CCCCC/N=C(\N)N
InChI InChI=1S/C16H23N3O4/c1-2-22-15(21)12-7-9-13(10-8-12)23-14(20)6-4-3-5-11-19-16(17)18/h7-10H,2-6,11H2,1H3,(H4,17,18,19)^N Key:YKGYIDJEEQRWQH-UHFFFAOYSA-N^N
^NY (what is this?) (verify)

Gabexate is a serine protease inhibitor which is used therapeutically (as gabexate mesilate) in the treatment of pancreatitis, disseminated intravascular coagulation,^[1] and as a regional anticoagulant for haemodialysis.^[2]

References[edit]

^ Yuksel M, Okajima K, Uchiba M, Okabe H (2003). "Gabexate mesilate, a synthetic protease inhibitor, inhibits lipopolysaccharide-induced tumor necrosis factor-alpha production by inhibiting activation of both nuclear factor-kappaB and activator protein-1 in human monocytes". J. Pharmacol. Exp. Ther. 305 (1): 298–305. doi:10.1124/jpet.102.041988. PMID 12649382. S2CID 23518949.

This drug article relating to the blood and blood forming organs is a stub. You can help Wikipedia by expanding it.