Fludyer inherited wealth from his father, one of the richest clothiers of his time, and social rank from his mother. He was educated at Westminster School, and sent on the Grand Tour with his elder brother Samuel.
Fludyer inherited the interests of his father, Sir Samuel, at Chippenham, which he represented from 1783 to 1802. He is referred to, as F——r, in a political cartoon of 1784, which caricatures John Robinson, Treasury Secretary to the Fox–North coalition, offering bribes to MPs.[3]
Fludyer fell out with the Corporation of Chippenham and gave his interest there to John Maitland. He served as a stopgap member for Appleby in 1818–19 at the behest of William Lowther, 1st Earl of Lonsdale, a family connection (the Earl was married to another daughter of the 9th Earl of Westmorland).
Mary (died 1830), married in 1818 Arthur George Onslow, and became Countess of Onslow.
Caroline (died 1824), married in 1818 John Cust, 1st Earl Brownlow, as his second wife. In a marriage of first cousins, her daughter Katherine Anne married a son Arthur George Onslow (1820–1856), courtesy title Viscount Cranley, of her sister Mary.[5]
The second baronet owned a house at Lee, Kent, and another in Fludyer Street, parallel to Downing Street in Westminster. In 1797 George Fludyer is recorded as living in Thistleton, in Rutland.[8]
Fludyer moved to be near the family of his mother Caroline, who died in 1803. In 1801 she inherited land at Ayston from her brother, George Brydges Brudenell;[9] and with it the patronage of livings in the two villages. On her death, Fludyer inherited land at Ayston and Wardley.[10] In 1807 he had a large house, Ayston Hall, built near the church in Ayston, and lived there until he died.