Hegedus indole synthesis | |
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Named after | Louis S. Hegedus |
Reaction type | Ring forming reaction |
The Hegedus indole synthesis is a name reactioninorganic chemistry that allows for the generation of indoles through palladium(II)-mediated oxidative cyclization of ortho-alkenyl anilines.[1][2][3][4][5][6] The reaction can still take place for tosyl-protected amines.[4]
2-Allylaniline can be converted to 2-Methylindole using the Hegedus indole synthesis.[1]
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