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F r o m W i k i p e d i a , t h e f r e e e n c y c l o p e d i a
Histoplasma is a genus of fungi in the order Onygenales .[1] Species are known human pathogens producing yeast -like states under pathogenic conditions. They are the causative agents of histoplasmosis in humans and epizootic lymphangitis in horses.[2]
Forms and stages [ edit ]
Histoplasma species have two forms: their environmental form is hyphal with microconidia and tuberculate macroconidia while their pathogenic form is a small intracellular yeast with a narrow neck and no bud with no capsule.[3] Infection occurs through inhalation of microconidia or small mycelial fragments. The dimorphic mold-yeast transforms and enters host macrophages and proliferates within them. Infections are most often seen in immunodeficient individuals.[4]
Species are mainly found in the Ohio and Mississippi River Valleys in the United States (H.ohiense and H. mississippiense ) as well as Central (H. capsulatum ) and South America (H. suramericanum ), Africa (H. duboisii ), Asia, and Australia.[5] [6]
References [ edit ]
^ Jiang Y, Dukik K, Munoz JF, Sigler L, Schwartz IS, Govender NP, Kenyon C, Feng P, van den Ende BG, Stielow JB, Stchigel AM, Lu H, de Hoog S (2018). "Phylogeny, ecology and taxonomy of systemic pathogens and their relatives in Ajellomycetaceae (Onygenales): Blastomyces , Emergomyces , Emmonsia , Emmonsiellopsis " . Fungal Diversity . 90 : 245–291. doi :10.1007/s13225-018-0403-y . hdl :10067/1520590151162165141 .
^ OIE Manual of Diagnostic Tests and Vaccines for Terrestrial Animals 2004 Chapter 2.5.13, "Archived copy" . Archived from the original on 2007-08-04. Retrieved 2007-06-14 .{{cite web }}
: CS1 maint: archived copy as title (link )
^ Hutton, JP (April 1985). "Hyphal forms of Histoplasma capsulatum . A common manifestation of intravascular infections" . Archives of Pathology and Laboratory Medicine . 109 (4 ): 330–332. PMID 3885898 – via Pubmed.
^ Lopez, CE (Oct 2006). "Dimorphism and pathogenesis of Histoplasma capsulatum " . Revista Argentina de Microbiologia . 38 (4 ): 235–242. PMID 17370580 – via Pubmed.
^ "Histoplasmosis" . Centers for Disease Control and Prevention . 28 October 2020. Retrieved 27 January 2021 .
^ Sepúlveda VE, Márquez R, Turissini DA, Goldman WE, Matute DR (2017). "Genome sequences reveal cryptic speciation in the human pathogen Histoplasma capsulatum " . mBio . 8 (6 ): e01339-17. doi :10.1128/mbio.01339-17 . PMC 5717386 . PMID 29208741 .
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R e t r i e v e d f r o m " https://en.wikipedia.org/w/index.php?title=Histoplasma&oldid=1210909175 "
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