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Contents

   



(Top)
  


1 References  




2 Further reading  













IFNA14






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From Wikipedia, the free encyclopedia
  

IFNA14

Identifiers

Aliases

IFNA14, IFN-alphaH, LEIF2H, interferon alpha 14

External IDs

OMIM: 147579; MGI: 2667155; HomoloGene: 122139; GeneCards: IFNA14; OMA:IFNA14 - orthologs

Gene location (Human)

Chromosome 9 (human)

Chr.

Chromosome 9 (human)[1]

Chromosome 9 (human)

Genomic location for IFNA14

Genomic location for IFNA14

Band

9p21.3

Start

21,239,002 bp[1]

End

21,240,005 bp[1]

Gene location (Mouse)

Chromosome 4 (mouse)

Chr.

Chromosome 4 (mouse)[2]

Chromosome 4 (mouse)

Genomic location for IFNA14

Genomic location for IFNA14

Band

4 C4|4 42.02 cM

Start

88,561,878 bp[2]

End

88,562,696 bp[2]

Bgee

Mouse (ortholog)

  • renal cortex

  • muscle of leg

  • kidney

  • gastrocnemius muscle

  • multicellular organism
    • embryo

  • embryo

    • More reference expression data

    BioGPS

    n/a

    Molecular function

  • type I interferon receptor binding
  • cytokine receptor binding

    • Cellular component

  • extracellular space

    • Biological process

  • B cell differentiation
  • defense response
  • B cell proliferation
  • blood coagulation
  • positive regulation of peptidyl-serine phosphorylation of STAT protein
  • humoral immune response
  • adaptive immune response
  • defense response to virus
  • type I interferon signaling pathway
  • response to exogenous dsRNA
  • T cell activation involved in immune response
  • innate immune response
  • cytokine-mediated signaling pathway
  • regulation of signaling receptor activity

    • Sources:Amigo / QuickGO

    Species

    Human

    Mouse

    Entrez

    3448

    230396

    Ensembl

    ENSG00000228083

    ENSMUSG00000063376

    UniProt

    P01570

    Q80SU4

    RefSeq (mRNA)

    NM_002172

    NM_177347

    RefSeq (protein)

    NP_002163

    NP_796321

    Location (UCSC)

    Chr 9: 21.24 – 21.24 Mb

    Chr 4: 88.56 – 88.56 Mb

    PubMed search

    [3]

    [4]

    Wikidata

    Interferon alpha-14 is a protein that in humans is encoded by the IFNA14 gene.[5][6]


    References[edit]

    1. ^ a b c GRCh38: Ensembl release 89: ENSG00000228083 – Ensembl, May 2017
  • ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000063376 – Ensembl, May 2017
  • ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  • ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  • ^ Olopade OI, Bohlander SK, Pomykala H, Maltepe E, Van Melle E, Le Beau MM, Diaz MO (Dec 1992). "Mapping of the shortest region of overlap of deletions of the short arm of chromosome 9 associated with human neoplasia". Genomics. 14 (2): 437–43. doi:10.1016/S0888-7543(05)80238-1. PMID 1385305.
  • ^ "Entrez Gene: IFNA14 interferon, alpha 14".

    • Further reading[edit]

  • Dawson SJ, White LA (1992). "Treatment of Haemophilus aphrophilus endocarditis with ciprofloxacin". J. Infect. 24 (3): 317–20. doi:10.1016/S0163-4453(05)80037-4. PMID 1602151.
  • Henco K, Brosius J, Fujisawa A, et al. (1985). "Structural relationship of human interferon alpha genes and pseudogenes". J. Mol. Biol. 185 (2): 227–60. doi:10.1016/0022-2836(85)90401-2. PMID 4057246.
  • Goeddel DV, Leung DW, Dull TJ, et al. (1981). "The structure of eight distinct cloned human leukocyte interferon cDNAs". Nature. 290 (5801): 20–6. Bibcode:1981Natur.290...20G. doi:10.1038/290020a0. PMID 6163083. S2CID 1900300.
  • Lawn RM, Adelman J, Dull TJ, et al. (1981). "DNA sequence of two closely linked human leukocyte interferon genes". Science. 212 (4499): 1159–62. Bibcode:1981Sci...212.1159L. doi:10.1126/science.6165082. PMID 6165082.
  • Tiefenbrun N, Melamed D, Levy N, et al. (1996). "Alpha interferon suppresses the cyclin D3 and cdc25A genes, leading to a reversible G0-like arrest". Mol. Cell. Biol. 16 (7): 3934–44. doi:10.1128/MCB.16.7.3934. PMC 231390. PMID 8668211.
  • Hussain M, Gill DS, Liao MJ (1997). "Identification of interferon-alpha 7, -alpha 14, and -alpha 21 variants in the genome of a large human population". J. Interferon Cytokine Res. 16 (10): 853–9. doi:10.1089/jir.1996.16.853. PMID 8910771.
  • Nyman TA, Tölö H, Parkkinen J, Kalkkinen N (1998). "Identification of nine interferon-alpha subtypes produced by Sendai virus-induced human peripheral blood leucocytes". Biochem. J. 329 (Pt 2): 295–302. doi:10.1042/bj3290295. PMC 1219044. PMID 9425112.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.

    • Chemokine

    CSF

    Erythropoietin

  • Asialo erythropoietin
  • Carbamylated erythropoietin
  • CNTO-530
  • Darbepoetin alfa
  • Epoetin alfa
  • Epoetin beta
  • Epoetin delta
  • Epoetin epsilon
  • Epoetin gamma
  • Epoetin kappa
  • Epoetin omega
  • Epoetin theta
  • Epoetin zeta
  • Erythropoietin (EPO)
  • Erythropoietin-Fc
  • Methoxy polyethylene glycol-epoetin beta (CERA/Mircera)
  • Peginesatide
  • Pegol sihematide (EPO-018B)

    • G-CSF (CSF3)

  • Granulocyte colony-stimulating factor
  • Lenograstim
  • Leridistim
  • Lipegfilgrastim
  • Nartograstim
  • Pegfilgrastim
  • Pegnartograstim

    • GM-CSF (CSF2)

  • Granulocyte macrophage colony-stimulating factor
  • Milodistim
  • Molgramostim
  • Regramostim
  • Sargramostim

    • M-CSF (CSF1)

  • Interleukin-34
  • Lanimostim
  • Macrophage colony-stimulating factor
  • Mirimostim

    • SCF (c-Kit)

    Thrombopoietin

  • Pegacaristim
  • Promegapoietin
  • Romiplostim
  • Thrombopoietin (THPO, MGDF)

    • Interferon

    IFNAR (α/β, I)

  • Interferon alpha (interferon alfa, IFN-α)
  • Interferon alfa (IFNA1, IFNA2, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA21)
  • Interferon alfa 2a
  • Interferon alfa 2b
  • Interferon alfa n1
  • Interferon alfacon-1
  • Interferon alpha-n3
  • Interferon beta (IFN-β) (IFNB1, IFNB3)
  • Interferon beta 1a
  • Interferon beta 1b
  • Interferon kappa (IFN-ε/κ/τ/ζ, IFNK)
  • Interferon omega (IFN-ω, IFNW1)
  • Peginterferon alfa-2a
  • Peginterferon alfa-2b

    • IFNGR (γ, II)

  • Interferon gamma 1b

    • IFNLR (λ, III)

    • See IL-28R (IFNLR) here instead.

    Interleukin

    TGFβ

    TNF

    Others

    JAK
    (inhibitors)

  • Filgotinib
  • Momelotinib
  • Oclacitinib
  • Peficitinib
  • Ruxolitinib
  • Tofacitinib (tasocitinib)
  • Upadacitinib

    • JAK2

  • AZD-1480
  • Baricitinib
  • CHZ868
  • Cucurbitacin I (elatericin B, JSI-124)
  • CYT387
  • Lestaurtinib
  • NSC-7908
  • NSC-33994
  • Pacritinib
  • Peficitinib
  • Ruxolitinib
  • SD-1008
  • Tofacitinib (tasocitinib)

    • JAK3

  • Decernotinib (VX-509)
  • Peficitinib
  • Ritlecitinib
  • TCS-21311
  • Tofacitinib (tasocitinib)
  • WHI-P 154
  • ZM-39923
  • ZM-449829

    • TYK2

    Others

  • FMS-like tyrosine kinase 3 ligand (FLT3L)
  • Leukemia/leukocyte inhibitory factor (LIF)
  • Oncostatin M (OSM)
  • Thymic stromal lymphopoietin (TSLP)


    • Stub icon

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    • Retrieved from "https://en.wikipedia.org/w/index.php?title=IFNA14&oldid=1193919189"
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    ●This page was last edited on 6 January 2024, at 08:02 (UTC).
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