Jump to content
 







Main menu
    


Navigation  


●Main page
 ●Contents
 ●Current events
 ●Random article
 ●About Wikipedia
 ●Contact us
 ●Donate
  



Contribute  


●Help
 ●Learn to edit
 ●Community portal
 ●Recent changes
 ●Upload file
  







Search  

































●Create account

●Log in
 









●Create account
 ● Log in
  



Pages for logged out editors learn more  


●Contributions
 ●Talk
  


















Contents

   



(Top)
  


1 References  




2 Further reading  













IFNA16






●العربية
 ●مصرى
 ●Татарча / tatarça
 ●Українська
  
Edit links
  








●Article
 ●Talk
  
















●Read
 ●Edit
 ●View history
  







Tools
    


Actions  


●Read
 ●Edit
 ●View history
  



General  


●What links here
 ●Related changes
 ●Upload file
 ●Special pages
 ●Permanent link
 ●Page information
 ●Cite this page
 ●Get shortened URL
 ●Download QR code
 ●Wikidata item
  



Print/export  


●Download as PDF
 ●Printable version
  















Appearance
    

 





From Wikipedia, the free encyclopedia
  

IFNA16
Identifiers
AliasesIFNA16, IFN-alphaO, IFN-alpha-16, interferon, alpha 16, interferon alpha 16
External IDsOMIM: 147580; MGI: 2667155; HomoloGene: 105364; GeneCards: IFNA16; OMA:IFNA16 - orthologs
Orthologs
SpeciesHumanMouse
Entrez

3449

230396

Ensembl

ENSG00000147885

ENSMUSG00000063376

UniProt

P05015

Q80SU4

RefSeq (mRNA)

NM_002173

NM_177347

RefSeq (protein)

NP_002164

NP_796321

Location (UCSC)Chr 9: 21.22 – 21.22 MbChr 4: 88.56 – 88.56 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interferon alpha-16, also known as IFN-alpha-16, is a protein that in humans is encoded by theIFNA16 gene.[5][6]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000147885 – Ensembl, May 2017
  • ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000063376 – Ensembl, May 2017
  • ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  • ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  • ^ "Entrez Gene: interferon".
  • ^ Olopade OI, Bohlander SK, Pomykala H, Maltepe E, Van Melle E, Le Beau MM, Diaz MO (October 1992). "Mapping of the shortest region of overlap of deletions of the short arm of chromosome 9 associated with human neoplasia". Genomics. 14 (2): 437–43. doi:10.1016/S0888-7543(05)80238-1. PMID 1385305.

    • Further reading[edit]

  • Chen YH, Böck G, Vornhagen R, Steindl F, Katinger H, Dierich MP (1994). "HIV-1 gp41 enhances major histocompatibility complex class I and ICAM-1 expression on H9 and U937 cells". Int. Arch. Allergy Immunol. 104 (3): 227–31. doi:10.1159/000236670. PMID 7913356.
  • Dianzani F, Castilletti C, Gentile M, Gelderblom HR, Frezza F, Capobianchi MR (1998). "Effects of IFN alpha on late stages of HIV-1 replication cycle". Biochimie. 80 (8–9): 745–54. doi:10.1016/S0300-9084(99)80028-5. PMID 9865497.
  • Zagury JF, Chams V, Lachgar A, Achour A, Bizzini B, Burny A, Zagury D, Feldman M (1995). "Are CD4 and Fas peptide identities of gp120 relevant to the molecular basis of AIDS pathogenesis?". Cell Death Differ. 2 (1): 23–32. PMID 17180012.
  • Myers MP, Andersen JN, Cheng A, Tremblay ML, Horvath CM, Parisien JP, Salmeen A, Barford D, Tonks NK (2001). "TYK2 and JAK2 are substrates of protein-tyrosine phosphatase 1B". J. Biol. Chem. 276 (51): 47771–4. doi:10.1074/jbc.C100583200. PMID 11694501.
  • Cicala C, Arthos J, Selig SM, Dennis Jr G, Hosack DA, Van Ryk D, Spangler ML, Steenbeke TD, Khazanie P (2002). "HIV envelope induces a cascade of cell signals in non-proliferating target cells that favor virus replication". Proc. Natl. Acad. Sci. U.S.A. 99 (14): 9380–5. Bibcode:2002PNAS...99.9380C. doi:10.1073/pnas.142287999. PMC 123149. PMID 12089333.
  • Schmidt B, Ashlock BM, Foster H, Fujimura SH, Levy JA (2005). "HIV-infected cells are major inducers of plasmacytoid dendritic cell interferon production, maturation, and migration". Virology. 343 (2): 256–66. doi:10.1016/j.virol.2005.09.059. PMID 16278001.
  • Kinzl P, Otani T, Benz R, Minowada J (1997). "Interferon-alpha and -gamma differentially reduce rapid immature T-cell death by contact with HIV-1 carrier cell clones in vitro". Microbiol. Immunol. 41 (9): 709–16. doi:10.1111/j.1348-0421.1997.tb01915.x. PMID 9343822. S2CID 85304106.
  • Francis ML, Meltzer MS (1993). "Induction of IFN-alpha by HIV-1 in monocyte-enriched PBMC requires gp120-CD4 interaction but not virus replication". J. Immunol. 151 (4): 2208–16. doi:10.4049/jimmunol.151.4.2208. PMID 8345204.
  • Peng G, Lei KJ, Jin W, Greenwell-Wild T, Wahl SM (2006). "Induction of APOBEC3 family proteins, a defensive maneuver underlying interferon-induced anti-HIV-1 activity". J. Exp. Med. 203 (1): 41–6. doi:10.1084/jem.20051512. PMC 2118075. PMID 16418394.
  • Silva LK, Blanton RE, Parrado AR, Melo PS, Morato VG, Reis EA, Dias JP, Castro JM, Vasconcelos PF (2010). "Dengue hemorrhagic fever is associated with polymorphisms in JAK1". Eur. J. Hum. Genet. 18 (11): 1221–7. doi:10.1038/ejhg.2010.98. PMC 2950898. PMID 20588308.
  • Yang XR, Liang X, Pfeiffer RM, Wheeler W, Maeder D, Burdette L, Yeager M, Chanock S, Tucker MA (2010). "Associations of 9p21 variants with cutaneous malignant melanoma, nevi, and pigmentation phenotypes in melanoma-prone families with and without CDKN2A mutations". Fam. Cancer. 9 (4): 625–33. doi:10.1007/s10689-010-9356-3. PMC 3233727. PMID 20574843.
  • Popik W, Hesselgesser JE, Pitha PM (1998). "Binding of human immunodeficiency virus type 1 to CD4 and CXCR4 receptors differentially regulates expression of inflammatory genes and activates the MEK/ERK signaling pathway". J. Virol. 72 (8): 6406–13. doi:10.1128/JVI.72.8.6406-6413.1998. PMC 109793. PMID 9658081.
  • Gessani S, Borghi P, Fantuzzi L, Varano B, Conti L, Puddu P, Belardelli F (1997). "Induction of cytokines by HIV-1 and its gp120 protein in human peripheral blood monocyte/macrophages and modulation of cytokine response during differentiation". J. Leukoc. Biol. 62 (1): 49–53. doi:10.1002/jlb.62.1.49. PMID 9225992. S2CID 31546644.
  • Del Cornò M, Gauzzi MC, Penna G, Belardelli F, Adorini L, Gessani S (2005). "Human immunodeficiency virus type 1 gp120 and other activation stimuli are highly effective in triggering alpha interferon and CC chemokine production in circulating plasmacytoid but not myeloid dendritic cells". J. Virol. 79 (19): 12597–601. doi:10.1128/JVI.79.19.12597-12601.2005. PMC 1211530. PMID 16160188.
  • Sen GC, Lengyel P (1992). "The interferon system. A bird's eye view of its biochemistry". J. Biol. Chem. 267 (8): 5017–20. doi:10.1016/S0021-9258(18)42719-6. PMID 1371992.
  • Taoufik Y, Lantz O, Wallon C, Charles A, Dussaix E, Delfraissy JF (1997). "Human immunodeficiency virus gp120 inhibits interleukin-12 secretion by human monocytes: an indirect interleukin-10-mediated effect". Blood. 89 (8): 2842–8. doi:10.1182/blood.V89.8.2842. PMID 9108403.
  • Conti L, Fantuzzi L, Del Cornò M, Belardelli F, Gessani S (2004). "Immunomodulatory effects of the HIV-1 gp120 protein on antigen presenting cells: implications for AIDS pathogenesis". Immunobiology. 209 (1–2): 99–115. doi:10.1016/j.imbio.2004.02.008. PMID 15481145.
  • Schols D, De Clercq E (1996). "Human immunodeficiency virus type 1 gp120 induces anergy in human peripheral blood lymphocytes by inducing interleukin-10 production". J. Virol. 70 (8): 4953–60. doi:10.1128/JVI.70.8.4953-4960.1996. PMC 190447. PMID 8764000.
  • Ankel H, Capobianchi MR, Frezza F, Castilletti C, Dianzani F (1996). "Interferon induction by HIV-1-infected cells: a possible role of sulfatides or related glycolipids". Virology. 221 (1): 113–9. doi:10.1006/viro.1996.0357. PMID 8661419.


    • Stub icon

    This article on a gene on human chromosome 9 is a stub. You can help Wikipedia by expanding it.

  • t
  • e

    • Retrieved from "https://en.wikipedia.org/w/index.php?title=IFNA16&oldid=1199455311"
    Categories: 
    ●Genes on human chromosome 9
     ●Human chromosome 9 gene stubs
     Hidden categories: 
    ●Articles with short description
     ●Short description matches Wikidata
     ●All stub articles
      


    ●This page was last edited on 27 January 2024, at 03:14 (UTC).
    ●Text is available under the Creative Commons Attribution-ShareAlike License 4.0; additional terms may apply. By using this site, you agree to the Terms of Use and Privacy Policy. Wikipedia® is a registered trademark of the Wikimedia Foundation, Inc., a non-profit organization.


    ●Privacy policy
    ●About Wikipedia
    ●Disclaimers
    ●Contact Wikipedia
    ●Code of Conduct
    ●Developers
    ●Statistics
    ●Cookie statement
    ●Mobile view


    Wikimedia Foundation
    Powered by MediaWiki