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Contents

   



(Top)
 


1 Signs and symptoms  





2 Causes  





3 Diagnosis  





4 Treatment  





5 See also  





6 References  





7 Further reading  





8 External links  














Idiopathic granulomatous hepatitis







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From Wikipedia, the free encyclopedia
 


Idiopathic granulomatous hepatitis
SpecialtyHepatology

Idiopathic granulomatous hepatitis is a rare medical condition characterized by granulomas in the liver, recurrent fever, myalgia, and fatigue. The condition is not a true hepatitis, and some experts believe it is a variant of sarcoidosis.[1][2]

Signs and symptoms[edit]

Idiopathic granulomatous hepatitis is marked by granuloma in the liver and recurrent fevers.[3] Fatigue and weight loss are other common symptoms.[4]

Causes[edit]

Granulomas in the liver often correspond to a systemic illness that the patient had previously been diagnosed with. Liver granulomas, however, could be a symptom of an unidentified systemic illness or they might not have a discernible underlying cause.[3]

Diagnosis[edit]

Establishing the diagnosis can be difficult because it needs to rule out other conditions that can cause hepatic granulomas, like lymphoma, sarcoidosis, drug allergies, and infections by fungiormycobacteria.[3]

Treatment[edit]

Idiopathic granulomatous hepatitis is treated with methotrexate along with additional immunosuppressive medications such as vinblastine, cyclophosphamide, and chlorambucil.[4]

See also[edit]

References[edit]

  1. ^ Tholey, Danielle (May 3, 2023). "Hepatic and Biliary Disorders". Merck Manuals Professional Edition. Retrieved January 9, 2024.
  • ^ "Hepatic Granulomas". Hepatitis Central. April 10, 2015. Retrieved January 9, 2024.
  • ^ a b c Lee, Yong Hong; Choi, Chang Hyon; Lee, Nam Su; Cheon, Gob Jin; Lee, Jae Sung; Shin, Joong Ho; Woo, Jun Hee (July 31, 1996). "Case Report : Idiopathic Granulomatous Hepatitis Manifested with Fever of Unknown Origin". The Korean Journal of Internal Medicine. 11 (2). Korean Association of Internal Medicine: 161–164. doi:10.3904/kjim.1996.11.2.161. ISSN 1226-3303. PMC 4532012. PMID 8854654.
  • ^ a b Knox, Tamsin A. (1995-04-15). "Methotrexate Treatment of Idiopathic Granulomatous Hepatitis". Annals of Internal Medicine. 122 (8): 592–595. doi:10.7326/0003-4819-122-8-199504150-00006. ISSN 0003-4819. PMID 7887553. S2CID 24241373.
  • Further reading[edit]

    External links[edit]


    Retrieved from "https://en.wikipedia.org/w/index.php?title=Idiopathic_granulomatous_hepatitis&oldid=1194590294"

    Categories: 
    Ailments of unknown cause
    Abdominal pain
    Rare diseases
    Monocyte- and macrophage-related cutaneous conditions
    Autoimmune diseases
    Diseases of liver
    Hidden categories: 
    Articles with short description
    Short description matches Wikidata
     



    This page was last edited on 9 January 2024, at 19:42 (UTC).

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