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Idiopathic granulomatous hepatitis is a rare medical condition characterized by granulomas in the liver, recurrent fever, myalgia , and fatigue. The condition is not a true hepatitis , and some experts believe it is a variant of sarcoidosis .[1] [2]
Signs and symptoms [ edit ]
Idiopathic granulomatous hepatitis is marked by granuloma in the liver and recurrent fevers .[3] Fatigue and weight loss are other common symptoms.[4]
Granulomas in the liver often correspond to a systemic illness that the patient had previously been diagnosed with. Liver granulomas, however, could be a symptom of an unidentified systemic illness or they might not have a discernible underlying cause.[3]
Diagnosis [ edit ]
Establishing the diagnosis can be difficult because it needs to rule out other conditions that can cause hepatic granulomas, like lymphoma , sarcoidosis , drug allergies , and infections by fungi or mycobacteria .[3]
Treatment [ edit ]
Idiopathic granulomatous hepatitis is treated with methotrexate along with additional immunosuppressive medications such as vinblastine , cyclophosphamide , and chlorambucil .[4]
See also [ edit ]
References [ edit ]
^ a b c Lee, Yong Hong; Choi, Chang Hyon; Lee, Nam Su; Cheon, Gob Jin; Lee, Jae Sung; Shin, Joong Ho; Woo, Jun Hee (July 31, 1996). "Case Report : Idiopathic Granulomatous Hepatitis Manifested with Fever of Unknown Origin" . The Korean Journal of Internal Medicine . 11 (2 ). Korean Association of Internal Medicine: 161–164. doi :10.3904/kjim.1996.11.2.161 . ISSN 1226-3303 . PMC 4532012 . PMID 8854654 .
^ a b Knox, Tamsin A. (1995-04-15). "Methotrexate Treatment of Idiopathic Granulomatous Hepatitis". Annals of Internal Medicine . 122 (8 ): 592–595. doi :10.7326/0003-4819-122-8-199504150-00006 . ISSN 0003-4819 . PMID 7887553 . S2CID 24241373 .
Further reading [ edit ]
External links [ edit ]
R e t r i e v e d f r o m " https://en.wikipedia.org/w/index.php?title=Idiopathic_granulomatous_hepatitis&oldid=1194590294 "
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● S h o r t d e s c r i p t i o n m a t c h e s W i k i d a t a
● T h i s p a g e w a s l a s t e d i t e d o n 9 J a n u a r y 2 0 2 4 , a t 1 9 : 4 2 ( U T C ) .
● T e x t i s a v a i l a b l e u n d e r t h e C r e a t i v e C o m m o n s A t t r i b u t i o n - S h a r e A l i k e L i c e n s e 4 . 0 ;
a d d i t i o n a l t e r m s m a y a p p l y . B y u s i n g t h i s s i t e , y o u a g r e e t o t h e T e r m s o f U s e a n d P r i v a c y P o l i c y . W i k i p e d i a ® i s a r e g i s t e r e d t r a d e m a r k o f t h e W i k i m e d i a F o u n d a t i o n , I n c . , a n o n - p r o f i t o r g a n i z a t i o n .
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