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1 See also  




2 References  













JWH-185






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From Wikipedia, the free encyclopedia
  

JWH-185
Legal status
Legal status
  • US: Schedule I
    • Identifiers

    • 3-[(4-Methoxy-1-naphthalenyl)methyl]-1-pentyl-1H-indole

    CAS Number
    ChemSpider
    UNII
    Chemical and physical data
    FormulaC25H27NO
    Molar mass357.497 g·mol−1
    3D model (JSmol)

    • CCCCCn1cc(c2c1cccc2)Cc3ccc(c4c3cccc4)OC

    • InChI=1S/C25H27NO/c1-3-4-9-16-26-18-20(22-11-7-8-13-24(22)26)17-19-14-15-25(27-2)23-12-6-5-10-21(19)23/h5-8,10-15,18H,3-4,9,16-17H2,1-2H3

    • Key:OTYBPWBZUDBUQS-UHFFFAOYSA-N

    JWH-185 is a synthetic cannabinoid receptor ligand from the naphthoylindole family. It is the carbonyl-reduced derivative of related compound JWH-081. The binding affinity of JWH-185 for the CB1 receptor is reported as Ki = 17 ± 3 nM.[1]

    In the United States, all CB1 receptor agonists of the 3-(1-naphthylmethane)indole class such as JWH-185 are Schedule I Controlled Substances.[2]

    See also[edit]

    References[edit]

    1. ^ Huffman JW, Mabon R, Wu MJ, Lu J, Hart R, Hurst DP, Reggio PH, Wiley JL, Martin BR (2003). "3-Indolyl-1-naphthylmethanes: new cannabimimetic indoles provide evidence for aromatic stacking interactions with the CB1 cannabinoid receptor". Bioorg. Med. Chem. 11 (4): 539–549. doi:10.1016/s0968-0896(02)00451-0. PMID 12538019. S2CID 29107765.
  • ^ 21 U.S.C. § 812: Schedules of controlled substances


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    • Retrieved from "https://en.wikipedia.org/w/index.php?title=JWH-185&oldid=1125083856"
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    ●This page was last edited on 2 December 2022, at 03:05 (UTC).
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