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(Top) 1 Interactions 2 References 3 Further reading

KIF13A

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KIF13A

Identifiers

Aliases

KIF13A, RBKIN, bA500C11.2, kinesin family member 13A

External IDs

OMIM: 605433; MGI: 1098264; HomoloGene: 22589; GeneCards: KIF13A; OMA:KIF13A - orthologs

Gene location (Human)

Chr.	Chromosome 6 (human)^[1]

Band	6p22.3	Start	17,759,183 bp^[1]
Band	6p22.3	End	17,987,635 bp^[1]

Gene location (Mouse)

Chr.	Chromosome 13 (mouse)^[2]

Band	13\|13 A5	Start	46,749,087 bp^[2]
Band	13\|13 A5	End	46,929,867 bp^[2]

RNA expression pattern

Bgee

Human

Mouse (ortholog)

Top expressed in

tendon of biceps brachii

Skeletal muscle tissue of rectus abdominis

Skeletal muscle tissue of biceps brachii

saphenous vein

internal globus pallidus

body of tongue

right ventricle

jejunum

synovial joint

nipple

Top expressed in

muscle of thigh

soleus muscle

retinal pigment epithelium

atrium

myocardium of ventricle

skeletal muscle tissue

genital tubercle

temporal muscle

digastric muscle

triceps brachii muscle

More reference expression data

BioGPS

n/a

Gene ontology
Molecular function	microtubule motor activity nucleotide binding microtubule binding ATPase activity protein binding ATP binding
Cellular component	cytoplasm endosome centrosome Golgi apparatus trans-Golgi network membrane membrane kinesin complex Golgi membrane microtubule organizing center midbody endosome membrane microtubule cytoskeleton intracellular anatomical structure
Biological process	plus-end-directed vesicle transport along microtubule cytoskeleton-dependent intracellular transport endosome to lysosome transport cell division melanosome organization microtubule-based movement vesicle cargo loading protein transport cell cycle intracellular protein transport Golgi to plasma membrane protein transport regulation of cytokinesis
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


63971


16553

Ensembl


ENSG00000137177


ENSMUSG00000021375

UniProt


Q9H1H9


Q9EQW7

RefSeq (mRNA)


NM_001105566 NM_001105567 NM_001105568 NM_001243423 NM_022113


NM_010617

RefSeq (protein)


NP_001099036 NP_001099037 NP_001099038 NP_001230352 NP_071396


NP_034747

Location (UCSC)

Chr 6: 17.76 – 17.99 Mb

Chr 13: 46.75 – 46.93 Mb

PubMed search

^[3]

^[4]

Wikidata

View/Edit Human

View/Edit Mouse

Kinesin-like protein KIF13A is a protein that in humans is encoded by the KIF13A gene.^[5]^[6]

Interactions[edit]

KIF13A has been shown to interact with AP1B1.^[5]

References[edit]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000137177 – Ensembl, May 2017

^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000021375 – Ensembl, May 2017

^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

^ ^a ^b Nakagawa T, Setou M, Seog D, Ogasawara K, Dohmae N, Takio K, Hirokawa N (Jan 2001). "A novel motor, KIF13A, transports mannose-6-phosphate receptor to plasma membrane through direct interaction with AP-1 complex". Cell. 103 (4): 569–81. doi:10.1016/S0092-8674(00)00161-6. PMID 11106728. S2CID 18245989.

^ "Entrez Gene: KIF13A kinesin family member 13A".

Further reading[edit]

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.

Hillier LD, Lennon G, Becker M, et al. (1997). "Generation and analysis of 280,000 human expressed sequence tags". Genome Res. 6 (9): 807–28. doi:10.1101/gr.6.9.807. PMID 8889549.

Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.

De Graeve F, Bahr A, Chatton B, Kedinger C (2000). "A murine ATFa-associated factor with transcriptional repressing activity". Oncogene. 19 (14): 1807–19. doi:10.1038/sj.onc.1203492. PMID 10777215.

Jamain S, Quach H, Fellous M, Bourgeron T (2001). "Identification of the human KIF13A gene homologous to Drosophila kinesin-73 and candidate for schizophrenia". Genomics. 74 (1): 36–44. doi:10.1006/geno.2001.6535. PMID 11374900.

Chen D, Pajovic S, Duckett A, et al. (2002). "Genomic amplification in retinoblastoma narrowed to 0.6 megabase on chromosome 6p containing a kinesin-like gene, RBKIN". Cancer Res. 62 (4): 967–71. PMID 11861365.

Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.

Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi:10.1038/nature02055. PMID 14574404.

Colland F, Jacq X, Trouplin V, et al. (2004). "Functional proteomics mapping of a human signaling pathway". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMC 442148. PMID 15231748.

Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243. S2CID 14294292.

This article on a gene on human chromosome 6 is a stub. You can help Wikipedia by expanding it.

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