White can respond 3.Nc3, 3.Nd2, or 3.Bd2. The game often transposes to a Nimzo-Indian Defence, a Dutch Defence, a Queen's Gambit Declined, an English Defence, or a Bogo-Indian Defence. 3.Nc3 is likely to transpose into one of those openings: 3...Nf6 (Nimzo-Indian), 3...f5 (Dutch; Korn gives 3...Bxc3+ 4.bxc3 f5!,[3] played by Buckle) 3...d5 (an unusual form of QGD), or 3...b6 (English). Black has the same options after 3.Nd2, except that 3...Nf6 4.Nf3 is a Bogo-Indian.
After 3.Bd2, Black can continue with 3...Bxd2+ into a line of the Bogo-Indian, and 3...a5 will also usually transpose to a Bogo-Indian when White plays Nf3. Or Black can allow White to play e4: 3...Qe7 4.e4 d5 (Black obtained a good game in Llanos–Hoffman, San Luis Clarin 1995 with 4...Nf6 5.a3 Bxd2+ 6.Nxd2 d6 7.Bd3 e5 8.d5 0-0)[4] 5.Bxb4 (5.e5 Timman–Spraggett, Montpellier 1985)[5][6] Qxb4+ 6.Qd2! Qxd2+ (if 6...Nc6 then 7.Nc3!) 7.Nxd2 with slight advantage for White.[7]