Blasingame signed with Vanderbilt as a linebacker in 2015. He started seven games in his freshman year, recording 12 total tackles. When he switched positions to halfback, the position he had played in high school, he experienced more success. Blasingame started 13 games, carrying the ball 97 times for 446 yards and 10 touchdowns. Starting 10 games as a junior, he rushed 45 times for 147 yards and no touchdowns. He also accumulated six receptions for 52 yards and a touchdown. Blasingame became a full-time starter during his senior season, taking 96 carries for 400 yards and five touchdowns, as well as racking up 25 catches for 320 yards and another touchdown.[4]
In 2019, Blasingame was named the Arthur Ashe Jr. Male Sports Scholar by Diverse: Issues In Higher Education.[5]
After going undrafted, the Minnesota Vikings signed Blasingame as an undrafted free agent on May 3, 2019.[7] He was waived on August 31, 2019, and was signed to the practice squad the next day.[8][9]
On November 13, 2019, the Tennessee Titans signed Blasingame to their active roster off the Vikings practice squad.[10] In Week 14, Blasingame caught two passes for 47 yards against the Oakland Raiders.[11]
Blasingame was placed on the reserve/COVID-19 list by the team on October 4, 2020,[12] and was activated from the list on October 16.[13]
Blasingame signed a one-year contract extension with the Titans on March 5, 2021.[14] He was placed on injured reserve on November 6, 2021.[15] He was activated on November 27.[16]
On March 22, 2022, Blasingame signed a one-year contract with the Chicago Bears.[17]
He signed a two-year contract extension on March 8, 2023.[18] Blasingame became the Bears' emergency running back during the team's week 5 matchup against the Washington Commanders following injuries to the team's three running backs. He carried the ball eight times for 26 yards. Blasingame only had three rushing attempts in his entire career prior to the game.[19]
