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The ldcC RNA motif is a conserved RNA structure that was discovered by bioinformatics.[1] ldcC motif RNAs are found in Bacillota and two species of Spirochaetota.
ldcC motif RNAs likely function as cis-regulatory elements, in view of their positions upstream of protein-coding genes. The genes presumably regulated by ldcC RNAs are decarboxylasesofarginine, ornithine, S-adenosylmethionine or other substrates. Endopeptidase C39A and potA (atransporterofspermidine/putrescine) is also relatively common. Thus, ldcC RNAs could regulate polyamine metabolism.
The ldcC motif might have a pseudoknot in its secondary structure, but it is unclear.
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