This is a list of songs which reached number one on the Billboard Mainstream Top 40 (or Pop Songs) chart in 2012.
During 2012, a total of 19 singles hit number-one on the charts.
| † | Indicates best-performing single of 2012 |
| Issue date | Song | Artist(s) | Ref. |
|---|---|---|---|
| January 7 | "We Found Love" | Rihanna featuring Calvin Harris | [1] |
| January 14 | [2] | ||
| January 21 | [3] | ||
| January 28 | [4] | ||
| February 4 | "It Will Rain" | Bruno Mars | [5] |
| February 11 | "The One That Got Away" | Katy Perry | [6] |
| February 18 | "Good Feeling" | Flo Rida | [7] |
| February 25 | "Set Fire to the Rain" | Adele | [8] |
| March 3 | [9] | ||
| March 10 | [10] | ||
| March 17 | [11] | ||
| March 24 | "Stronger (What Doesn't Kill You)" | Kelly Clarkson | [12] |
| March 31 | [13] | ||
| April 7 | [14] | ||
| April 14 | [15] | ||
| April 21 | "Glad You Came" | The Wanted | [16] |
| April 28 | "We Are Young" | Fun featuring Janelle Monáe | [17] |
| May 5 | [18] | ||
| May 12 | [19] | ||
| May 19 | [20] | ||
| May 26 | [21] | ||
| June 2 | "Somebody That I Used to Know" | Gotye featuring Kimbra | [22] |
| June 9 | [23] | ||
| June 16 | [24] | ||
| June 23 | "Call Me Maybe" | Carly Rae Jepsen | [25] |
| June 30 | [26] | ||
| July 7 | [27] | ||
| July 14 | "Payphone" | Maroon 5 featuring Wiz Khalifa | [28] |
| July 21 | [29] | ||
| July 28 | [30] | ||
| August 4 | [31] | ||
| August 11 | "Wide Awake" | Katy Perry | [32] |
| August 18 | [33] | ||
| August 25 | "Lights" † | Ellie Goulding | [34] |
| September 1 | "Wide Awake" | Katy Perry | [35] |
| September 8 | [36] | ||
| September 15 | "Give Your Heart a Break" | Demi Lovato | [37] |
| September 22 | "Whistle" | Flo Rida | [38] |
| September 29 | [39] | ||
| October 6 | "Blow Me (One Last Kiss)" | P!nk | [40] |
| October 13 | "One More Night" | Maroon 5 | [41] |
| October 20 | [42] | ||
| October 27 | [43] | ||
| November 3 | [44] | ||
| November 10 | [45] | ||
| November 17 | [46] | ||
| November 24 | [47] | ||
| December 1 | [48] | ||
| December 8 | "Die Young" | Ke$ha | [49] |
| December 15 | [50] | ||
| December 22 | [51] | ||
| December 29 | "Locked Out of Heaven" | Bruno Mars | [52] |
