List of notable protein secondary structure prediction programs
| Name | Method description | Type | Link | Initial release |
|---|---|---|---|---|
| RaptorX-SS8 | predict both 3-state and 8-state secondary structure using conditional neural fields from PSI-BLAST profiles | Webserver/downloadable | server download | 2011 |
| GOR | Information theory/Bayesian inference | Many implementations | Basic GOR GOR V | 2002 (GOR V) |
| Jpred | Multiple Neural network assignment from PSI-BLAST and HMMER profiles. Predicts secondary structure and solvent accessibility | Webserver | server and API | 1998 |
| PredictProtein | Profile-based neural network | Webserver | server | 1992 |
| PSIPRED | two feed-forward neural networks which perform an analysis on output obtained from PSI-BLAST | Webserver | server | 1999 |
