Born in Connecticut and raised in Brookline, Massachusetts, both of her parents were illustrators.[1] Shire began cooking as early as age four alongside her father. In 1971, she enrolled at Le Cordon Bleu in London.[2] She considers Jasper White to be her mentor,[3][4] and "her best cook friend in the world."[5]
When she returned from London, she became a line cook at Jacky Robert's Maison Robert. Within three years, she became head chef in 1974.[6]
Shire went to work at Seasons in The Bostonian Hotel in 1982 which led to national recognition and a James Beard Foundation "awarded (her) the coveted『Who’s Who of Food & Beverage』award in 1984."[6] It was here that she first met Jasper White. She worked under him as Executive Sous Chef and left, in 1985, as the Executive Chef[7] - the Bostonian's first female chef.[8]
In 1986, Shire went to Beverly Hills to open the Four Seasons hotel becoming the "first female Executive Chef in the Four Seasons Hotels & Resorts Company to open a luxury property."[6][8]
She returned to Boston and in 1989 Biba "opened to great fanfare."[8] Biba closed after 9/11 and reopened as Excelsior Restaurant and Shire was hired as Executive Chef.[7]
When Shire bought Locke-Ober with business partner Paul Licari in 2001, she became the historic restaurant's first female chef.[8]Jacky Robert was executive chef for two years beginning in 2001.[9] A ten-year lease was signed which they were unable to renew, forcing them to close. Shire was devastated, saying "They were for me 10 absolutely glorious years. Gourmet ranked us the 18th-best restaurant in the country, and named us to the 21 must-visit restaurants in your lifetime."[10]
Shire is married to former employee Uriel Pineda, and currently lives in Stoneham, Massachusetts. She has three children with former husband Tom Shire,[7] and a fourth child, Alex, with current husband Uriel Pineda. After cooking in restaurants in Spain, California and other locales, Alex Pineda worked as a chef with his mother at Scampo in Boston and in spring 2021, became the executive chef at The Landing, a seafood restaurant in Marblehead, Massachusetts.[12] He later competed on an Alton Brown-led tournament on Food Network's Chopped, winning his preliminary episode before subsequently being the first chef eliminated in the tournament finale episode.
