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Contents

   



(Top)
  


1 Applications  




2 See also  




3 References  




4 External links  













MOPS






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From Wikipedia, the free encyclopedia
  

This article is about the biochemical buffering agent. For information about other types of mops, see Mops.
MOPS
Names
Preferred IUPAC name

3-(Morpholin-4-yl)propane-1-sulfonic acid

Other names

3-(N-Morpholino)propanesulfonic acid,
3-Morpholinopropanesulfonic acid,
3-N-Morpholino propansulfonic acid,
4-Morpholinepropanesulfonic acid

Identifiers

CAS Number

3D model (JSmol)
ChemSpider
ECHA InfoCard 100.013.162 Edit this at Wikidata

PubChem CID
  • 2723950
    • UNII

    CompTox Dashboard (EPA)

    • InChI=1S/C7H15NO4S/c9-13(10,11)7-1-2-8-3-5-12-6-4-8/h1-7H2,(H,9,10,11) ☒N

      Key: DVLFYONBTKHTER-UHFFFAOYSA-N ☒N

    • InChI=1/C7H15NO4S/c9-13(10,11)7-1-2-8-3-5-12-6-4-8/h1-7H2,(H,9,10,11)

      Key: DVLFYONBTKHTER-UHFFFAOYAN

    • C1COCCN1CCCS(=O)(=O)O

    Properties

    Chemical formula

    		 C7H15NO4S
    Molar mass 209.26 g·mol−1
    Hazards
    GHS labelling:

    Pictograms

    		 GHS07: Exclamation mark

    Signal word

    		 Warning

    Hazard statements

    		 H315, H319, H335

    Precautionary statements

    		 P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501
    Safety data sheet (SDS) MSDS

    Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

    ☒N verify (what is checkY☒N ?)

    Infobox references

    MOPS (3-(N-morpholino)propanesulfonic acid) is a buffer introduced in the 1960s, one of the twenty Good's buffers. It is a structural analog to MES,[1] and like MES, its structure contains a morpholine ring. HEPES is a similar pH buffering compound that contains a piperazine ring. With a pKa of 7.20, MOPS is an excellent buffer for many biological systems at near-neutral pH.

    Applications[edit]

    MOPS is frequently used as a buffering agentinbiology and biochemistry. It has been tested and recommended for polyacrylamide gel electrophoresis.[2] Usage above 20 mM in mammalian cell culture work is not recommended.[3] MOPS buffer solutions become discolored (yellow) over time, but reportedly slight discoloration does not significantly affect the buffering characteristics.[4]

    See also[edit]

    References[edit]

    1. ^ Good, Norman E.; Winget, G. Douglas; Winter, Wilhelmina; Connolly, Thomas N.; Izawa, Seikichi; Singh, Raizada M. M. (1966). "Hydrogen Ion Buffers for Biological Research". Biochemistry. 5 (2): 467–77. doi:10.1021/bi00866a011. PMID 5942950.
  • ^ Thomas, J; Hodes, ME (1981). "A new discontinuous buffer system for the electrophoresis of cationic proteins at near-neutral pH". Analytical Biochemistry. 118 (1): 194–6. doi:10.1016/0003-2697(81)90178-0. PMID 6278979.
  • ^ Eagle, H. (1971). "Buffer Combinations for Mammalian Cell Culture". Science. 174 (4008): 500–3. Bibcode:1971Sci...174..500E. doi:10.1126/science.174.4008.500. PMID 5110427. S2CID 29876583.
  • ^ https://bostonbioproducts.com/products/mops-buffer-1-m-ph-74-bbm-74. {{cite web}}: Missing or empty |title= (help)

    • External links[edit]


    Retrieved from "https://en.wikipedia.org/w/index.php?title=MOPS&oldid=1164683225"
    Categories: 
    ●Buffer solutions
     ●Sulfonic acids
     ●4-Morpholinyl compounds
     Hidden categories: 
    ●CS1 errors: missing title
     ●CS1 errors: bare URL
     ●Chemical articles with multiple compound IDs
     ●Multiple chemicals in an infobox that need indexing
     ●Chemical articles with multiple PubChem CIDs
     ●Articles without EBI source
     ●Articles without KEGG source
     ●Articles with changed ChemSpider identifier
     ●ECHA InfoCard ID from Wikidata
     ●Articles with changed InChI identifier
     ●Chembox having GHS data
     ●Articles containing unverified chemical infoboxes
     ●Articles with short description
     ●Short description matches Wikidata
      


    ●This page was last edited on 10 July 2023, at 13:19 (UTC).
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