Before becoming a director, Ramesh played a supporting role in Bobby (2002).
Ramesh debuted as a director with the Kannada film Veera Kannadiga (2004), which was simultaneously made in Telugu as Andhrawala (2004). Veera Kannadiga was a box office success. His second film was Ajay (2006), a Kannada film which was a remake of Okkadu (2003).
Ramesh made his Telugu debut with Kantri (2008), starring N. T. Rama Rao Jr.. The film received mixed-to-negative reviews but was an aveage grosser at the box office. He then directed Billa (2009) with Prabhas,[3] which received positive reviews and became a box office hit.
Ramesh went on to direct Shakti (2011),[4] his second collaboration with NTR Jr. The film received negative reviews. Following this, he directed Shadow (2013).
Ramesh made his directorial comeback in 2023 with Bhola Shankar, starring Chiranjeevi. The film, a remake of the Tamil film Vedalam (2015), was panned by critics and became a box office bomb.
