Menefessi was located near modern Henchir-Djemmiah. In Roman times, it belonged to the North African Roman provinceofByzacena. The city was important enough to become a suffragan bishopric, but faded.
There are only two documented bishops of Menefessi.[2]
The Catholic Mensurio who attended the Carthage conference of 411, which brought together the Catholic and Donatist bishops of Roman Africa; on that occasion Menefessi did not have any Donatist bishops.
Servo took part in the synod gathered in Carthage by the Vandal king of Hunaric in 484, after which he was exiled.
Today Menefessi survives as a titular bishop's seat; the current titular bishop is José Trinidad González Rodríguez, former auxiliary bishop of Guadalajara. The diocese was nominally restored in 1933 as a Latin Catholic titular bishopric.
It has had the following incumbents, both of the lowest (episcopal) and intermediary (archiepiscopal) ranks :
Titular Bishop Ignatius John Doggett, Friars Minor (O.F.M.) (1969.06.06 – 1976.07.07)