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| Names | |
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| Preferred IUPAC name
2,2′-Methylenebis[6-(2H-1,2,3-benzotriazol-2-yl)-4-(2,4,4-trimethylpentan-2-yl)phenol] | |
| Other names
UV-360 | |
| Identifiers | |
3D model (JSmol) |
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| ChEMBL | |
| ChemSpider |
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| ECHA InfoCard | 100.100.550 
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PubChem CID |
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| UNII | |
CompTox Dashboard (EPA) |
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| Properties | |
| C41H50N6O2 | |
| Molar mass | 658.88 g/mol |
| Melting point | 195.7 °C (384.3 °F; 468.8 K) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
Bisoctrizole (INN[1]/USAN,[2] marketed by BASFasTinosorb M, by DSM Nutritional Products as Parsol Max , by Everlight Chemical as Eversorb M, and by MPI as Milestab 360, INCI methylene bis-benzotriazolyl tetramethylbutylphenol) is a phenolic benzotriazole that is added to sunscreens to absorb UV rays.[3] It is a broad-spectrum ultraviolet radiation absorber, absorbing UVB as well as UVA rays.[3] It also reflects and scatters UV.[citation needed]
Bisoctrizole is what is termed is a hybrid UV absorber, which has been described as an organic UV filter produced in microfine organic particles (< 200 nm),[verification needed][4][better source needed][5][non-primary source needed] like microfine zinc oxide and titanium dioxide.[dubious – discuss][citation needed] Where other organic UV absorbers dissolved in either the oily or aqueous phases, bisoctrizole dissolves poorly in both.[citation needed]
Hence, bisoctrizole is formulated in sunscreen preparations as a 50% suspension, the absorber added to the water phase,[contradictory] and mineral micropigments usually added to the oil phase.[citation needed] The bisoctrizole particles are stabilized by the surfactant decyl glucoside.[citation needed] The compound shows very little photodegradation, and has a stabilizing effect on other UV absorbers, octyl methoxycinnamate (octinoxate) in particular.[citation needed]
In primary research reports, bisoctrizole has been reported to minimally penetrate skin,[6][non-primary source needed] and has been described as lacking estrogenic effects in vitro.[7][non-primary source needed]
As of this date,[when?] bisoctrizole had not been approved by the U.S. Food and Drug Administration (FDA),[citation needed] but is approved in the EU and other parts of the world.[8][better source needed][9][10][full citation needed]
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Sunscreening agents approved by the US FDA or other agencies
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| UVA filters |
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| UVB filters |
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| UVA+UVB filters |
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