Jump to content

Main menu Navigation ●Main page ●Contents ●Current events ●Random article ●About Wikipedia ●Contact us ●Donate Contribute ●Help ●Learn to edit ●Community portal ●Recent changes ●Upload file

●Create account ●Log in ●Create account ● Log in Pages for logged out editors learn more ●Contributions ●Talk

(Top) 1 References

Moxisylyte

●العربية ●فارسی ●Magyar ●Српски / srpski ●Srpskohrvatski / српскохрватски ●Tiếng Việt Edit links ●Article ●Talk ●Read ●Edit ●View history Tools Actions ●Read ●Edit ●View history General ●What links here ●Related changes ●Upload file ●Special pages ●Permanent link ●Page information ●Cite this page ●Get shortened URL ●Download QR code ●Wikidata item Print/export ●Download as PDF ●Printable version In other projects ●Wikimedia Commons Appearance From Wikipedia, the free encyclopedia

Moxisylyte
Clinical data

Other names	Thymoxamine
AHFS/Drugs.com	International Drug Names
ATC code	G04BE06 (WHO) C04AX10 (WHO)
Identifiers
IUPAC name 4-[2-(Dimethylamino)ethoxy]-5-isopropyl-2-methylphenyl acetate
CAS Number	54-32-0^Y
PubChem CID	4260
DrugBank	DB09205^Y
ChemSpider	4110
UNII	PW8QYA7KI0
KEGG	D08239^Y
CompTox Dashboard (EPA)	DTXSID4023339
ECHA InfoCard	100.000.186
Chemical and physical data
Formula	C₁₆H₂₅NO₃
Molar mass	279.380 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES CC1=CC(=C(C=C1OC(=O)C)C(C)C)OCCN(C)C
InChI InChI=1S/C16H25NO3/c1-11(2)14-10-15(20-13(4)18)12(3)9-16(14)19-8-7-17(5)6/h9-11H,7-8H2,1-6H3 Key:VRYMTAVOXVTQEF-UHFFFAOYSA-N
(verify)

Moxisylyte, also known as thymoxamine, is a drug used in urology for the treatment of erectile dysfunction.^[1] It is an α₁-adrenergic antagonist.^[2] In the United Kingdom, Moxisylte is marketed as Opilon (Archimedes Pharma UK Ltd) and is used for the short-term treatment of primary Raynaud's syndrome. This is a condition where the fingers and toes become discoloured and is triggered by responses to cold, or emotional distress. Opilon tablets help by improving blood circulation to the extremities.^[3]^[4]

References[edit]

^ British National Formulary 69, Chapter2.6.4, page 142

^ Sakakibara R, Hattori T, Uchiyama T, et al. (March 2000). "Are alpha-blockers involved in lower urinary tract dysfunction in multiple system atrophy? A comparison of prazosin and moxisylyte". J. Auton. Nerv. Syst. 79 (2–3): 191–5. doi:10.1016/S0165-1838(99)00105-8. PMID 10699651.

^ British National Formulary 70, page 205

^ "Opilon tablets - Patient Information Leaflet (PIL) - (eMC)". www.medicines.org.uk.

v t e Peripheral vasodilators (C04)
Phenylethanolamine derivatives	Isoxsuprine Buphenine Bamethan
Alpha blockers	Non-selective Buflomedil Phentolamine Phenoxybenzamine Tolazoline Selective α₁-blockers Alfuzosin Doxazosin Prazosin Silodosin Tamsulosin Terazosin
Niacin and derivatives	Niacin Nicotinyl alcohol Inositol nicotinate Ciclonicate
Purine derivatives	Pentifylline Xantinol nicotinate Pentoxifylline Etofylline nicotinate
Ergot alkaloids	Ergoloid Nicergoline Dihydroergocristine
Other peripheral vasodilators	Cyclandelate Vincamine Moxisylyte Bencyclane Vinburnine Sulcotidil Naftidrofuryl Butalamine Visnadine Cetiedil Cinepazide Ifenprodil Azapetine Fasudil

Drugs for erectile dysfunction (G04BE) and premature ejaculation

For erectile dysfunction

Prostaglandins (E)	Alprostadil
PDE5 inhibitors	Avanafil Sildenafil Tadalafil Udenafil Vardenafil
Alpha blockers	Moxisylyte Phentolamine Yohimbine
Dopamine agonists	Apomorphine
Melanocortin agonists	Bremelanotide Melanotan II PL-6983
Others	Afrodor (acecarbromal, quebracho, vitamin E) Papaverine