NF-kappa-B-repressing factor is a protein that in humans is encoded by the NKRF gene.[5][6]
This gene encodes a transcription factor that interacts with specific negative regulatory elements (NREs) to mediate transcriptional repression of certain NK-kappa-B-responsive genes.
The protein localizes predominantly to the nucleolus with a small fraction found in the nucleoplasm and cytoplasm.[6]
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