Natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C), also known as NPR3, is an atrial natriuretic peptide receptor. In humans it is encoded by the NPR3 gene.[5]
The family of natriuretic peptides elicit a number of vascular, renal, and endocrine effects that are important in the maintenance of blood pressure and extracellular fluid volume. These effects are mediated by specific binding of the peptides to cell surface receptors in the vasculature, kidney, adrenal, and brain.[5]
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
PDB gallery
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1yk0: structure of natriuretic peptide receptor-C complexed with atrial natriuretic peptide
1jdp: Crystal Structure of Hormone/Receptor Complex
1yk1: structure of natriuretic peptide receptor-C complexed with brain natriuretic peptide
1jdn: Crystal Structure of Hormone Receptor
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