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Contents

   



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1 See also  




2 References  













O-4310






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From Wikipedia, the free encyclopedia
  

O-4310
Identifiers

  • 3-[2-(dimethylamino)ethyl]-6-fluoro-1-isopropyl-1H-indol-4-ol

CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC15H21FN2O
Molar mass264.344 g·mol−1
3D model (JSmol)

  • CC(C)N1C2=CC(F)=CC(O)=C2C(CCN(C)C)=C1

  • InChI=1S/C15H21FN2O/c1-10(2)18-9-11(5-6-17(3)4)15-13(18)7-12(16)8-14(15)19/h7-10,19H,5-6H2,1-4H3

  • Key:PAUIFMSQKOHMQT-UHFFFAOYSA-N

O-4310 (1-isopropyl-6-fluoro-psilocin) is a tryptamine derivative developed by Organix Inc which acts as a serotonin receptor agonist. It is claimed to have an EC50 of 5nM at 5-HT2A with 89% efficacy vs 5-HT, and 100x selectivity over 5-HT2C, while being apparently inactive at the 5-HT2B antitarget.[1][2]

See also[edit]

References[edit]

  1. ^ US 7655691, Kumaran G, Morency C, Roth B, Sard HP, Shuster L Xu L, "Indole compounds useful as serotonin selective agents.", published 11 May 2006, assigned to Organix Inc 
  • ^ Motaghinejad O, Motaghinejad M, Motevalian M, Rahimi-Sharbaf F, Beiranvand T (October 2017). "The effect of maternal forced exercise on offspring pain perception, motor activity and anxiety disorder: the role of 5-HT2 and D2 receptors and CREB gene expression". Journal of Exercise Rehabilitation. 13 (5): 514–525. doi:10.12965/jer.1734992.496. PMC 5667597. PMID 29114525.


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