Contents

OR2F1

Protein-coding gene in the species Homo sapiens

OR2F1
Identifiers
Aliases	OR2F1, OLF3, OR14-60, OR2F3, OR2F3P, OR2F4, OR2F5, OR7-139, OR7-140, 7M1-2, olfactory receptor family 2 subfamily F member 1 (gene/pseudogene), olfactory receptor family 2 subfamily F member 1
External IDs	OMIM: 608497; MGI: 3030287; HomoloGene: 128151; GeneCards: OR2F1; OMA:OR2F1 - orthologs
Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7q35 Start 143,954,844 bp[1] End 143,997,312 bp[1]
Gene location (Mouse) Chr. Chromosome 6 (mouse)[2] Band 6|6 B2.1 Start 42,716,305 bp[2] End 42,723,897 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in tibial arteries apex of heart smooth muscle tissue sural nerve placenta anterior cingulate cortex ascending aorta Descending thoracic aorta appendix right coronary artery n/a More reference expression data BioGPS n/a
Gene ontology Molecular function signal transducer activity G protein-coupled receptor activity olfactory receptor activity Cellular component membrane integral component of membrane plasma membrane Biological process response to stimulus signal transduction sensory perception of smell detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 26211 258016 Ensembl ENSG00000284866 ENSG00000213215 ENSMUSG00000095831 UniProt Q13607 Q7TRV7 RefSeq (mRNA) NM_012369 NM_001011799 RefSeq (protein) NP_036501 NP_001011799 Location (UCSC) Chr 7: 143.95 – 144 Mb Chr 6: 42.72 – 42.72 Mb PubMed search [3] [4]
Wikidata
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Olfactory receptor 2F1 is a protein that in humans is encoded by the OR2F1 gene.^[5][6]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.^[6]

• Olfactory receptor

• OR2F1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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