P2Y purinoceptor 14 is a protein that in humans is encoded by the P2RY14 gene.[5]
The product of this gene, P2Y14 belongs to the family of G-protein coupled receptors, which contains several receptor subtypes with different pharmacological selectivity for various adenosine and uridine nucleotides. This receptor is a P2Y purinergic receptor for UDP-glucose and other UDP-sugars coupled to G-proteins. It has been implicated in extending the known immune system functions of P2Y receptors by participating in the regulation of the stem cell compartment, and it may also play a role in neuroimmune function. Two transcript variants encoding the same protein have been identified for this gene.[5]
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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Receptor (ligands) |
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Transporter (blockers) |
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Enzyme (inhibitors) |
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See also: Receptor/signaling modulators |
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