Identifiers
(−)-N-Phenyl-7-(hydroxyimino)cyclopropa[b]chromen-1a-carboxamide
PubChem CID
Chemical and physical data
C17H14N2O3
294.310 g·mol−1
3D model (JSmol)
c4ccccc4NC(=O)C1(CC1C2=NO)Oc3ccccc23
PHCCC is a research drug which acts as a glutamate receptor ligand, particularly being a positive allosteric modulator at the mGluR4 subtype,[1] as well as an agonist at mGluR6.[2] It has anxiolytic effects in animal studies.[3] PHCCC and similar drugs have been suggested as novel treatments for Parkinson's disease.[4]
mGluR5Tooltip Metabotropic glutamate receptor 5
mGluR3Tooltip Metabotropic glutamate receptor 3
mGluR6Tooltip Metabotropic glutamate receptor 6
mGluR7Tooltip Metabotropic glutamate receptor 7
mGluR8Tooltip Metabotropic glutamate receptor 8