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Contents

   



(Top)
  


1 See also  




2 References  













PTI-1






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From Wikipedia, the free encyclopedia
  

PTI-1
Legal status
Legal status
  • DE: NpSG (Industrial and scientific use only)
  • UK: Class B
    • Identifiers

    • N,N-diethyl-N-((2-(1-pentyl-1H-indol-3-yl)thiazol-4-yl)methyl)ethanamine

    CAS Number
    ChemSpider
    UNII
    Chemical and physical data
    FormulaC21H29N3S
    Molar mass355.54 g·mol−1
    3D model (JSmol)

    • CCCCCN1C=C(C2=NC(CN(CC)CC)=CS2)C3=CC=CC=C31.Cl

    • InChI=1S/C21H29N3S.ClH/c1-4-7-10-13-24-15-19(18-11-8-9-12-20(18)24)21-22-17(16-25-21)14-23(5-2)6-3;/h8-9,11-12,15-16H,4-7,10,13-14H2,1-3H3;1H

    • Key:NPYOTZAJIONLKZ-UHFFFAOYSA-N

    PTI-1 (SGT-48) is an indole-based synthetic cannabinoid.[1] It is one of few synthetic cannabinoids containing a thiazole group and is closely related to PTI-2. These compounds may be viewed as simplified analogues of indole-3-heterocycle compounds originally developed by Organon and subsequently further researched by Merck.[2][3][4]

    See also[edit]

    References[edit]

    1. ^ "PTI-1". Cayman Chemical. Retrieved 8 July 2015.
  • ^ US 7700634, Adam-Worrall J, Morrison AJ, Wishart G, Kiyoi T, McArthur DR, "(Indol-3-yl) heterocycle derivatives as agonists of the cannabinoid CB1 receptor.", issued 20 April 2010, assigned to Organon NV 
  • ^ US 7763732, Paul David Ratcliffe PD, Adam-Worrall J, Morrison AJ, Francis SJ, Kiyoi T, "Indole Derivatives", issued 27 July 2010, assigned to Organon NV 
  • ^ Kiyoi T, Adam JM, Clark JK, Davies K, Easson AM, Edwards D, et al. (March 2011). "Discovery of potent and orally bioavailable heterocycle-based cannabinoid CB1 receptor agonists". Bioorganic & Medicinal Chemistry Letters. 21 (6): 1748–53. doi:10.1016/j.bmcl.2011.01.082. PMID 21316962.
    • Stub icon

    This cannabinoid related article is a stub. You can help Wikipedia by expanding it.

  • t
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    • Retrieved from "https://en.wikipedia.org/w/index.php?title=PTI-1&oldid=1082426145"
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    ●This page was last edited on 13 April 2022, at 03:51 (UTC).
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