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F r o m W i k i p e d i a , t h e f r e e e n c y c l o p e d i a
Paul B. Sigler ((1934-02-19 ) February 19, 1934 – (2000-01-11 ) January 11, 2000[7] [1] Biophysics and Biochemistry at Yale University .[3] [8] National Academy of Sciences , HHMI Investigator status, and Guggenheim [2] Helen Hay Whitney Fellowships.[5] Phospholipase A2 and trp repressor amongst many others.[1]
Biography [ edit ]
Prior to coming to Yale, he was a professor at the University of Chicago .[2] Columbia University in 1959 and his undergraduate degree from Princeton University in 1955.[2] NIH ,[5] Cambridge University at the Laboratory of Molecular Biology [2] David M. Blow [6] [2]
Memorials [ edit ]
A memorial plaque is located in front of the Bass Center for Structural Biology on Science Hill on the campus of Yale University . Yale has a Paul Sigler Memorial Prize for undergraduate research in Molecular Biophysics & Biochemistry.[9] [10] [11]
Paul Sigler died on January 11, 2000, at New Haven, Connecticut , US, about a month before his 66th birthday.[citation needed
Selected publications [ edit ]
Lambright, David G.; Sondek, John; Bohm, Andrew; Skiba, Nikolai P.; Hamm, Heidi E.; Sigler, Paul B. (1996). "The 2.0 Å crystal structure of a heterotrimeric G protein ". Nature . 379 (6563): 311–9. Bibcode :1996Natur.379..311L . doi :10.1038/379311a0 . PMID 8552184 . S2CID 4350943 .
Luisi, B. F.; Xu, W. X.; Otwinowski, Z.; Freedman, L. P.; Yamamoto, K. R.; Sigler, P. B. (1991). "Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA". Nature . 352 (6335): 497–505. Bibcode :1991Natur.352..497L . doi :10.1038/352497a0 . PMID 1865905 . S2CID 1919276 .
Braig, Kerstin; Otwinowski, Zbyszek; Hegde, Rashmi; Boisvert, David C.; Joachimiak, Andrzej; Horwich, Arthur L.; Sigler, Paul B. (1994). "The crystal structure of the bacterial chaperonln GroEL at 2.8 Å". Nature . 371 (6498): 578–86. Bibcode :1994Natur.371..578B . doi :10.1038/371578a0 . PMID 7935790 . S2CID 4341993 .
Kim, Youngchang; Geiger, James. H.; Hahn, Steven; Sigler, Paul B. (1993). "Crystal structure of a yeast TBP /TATA-box complex". Nature . 365 (6446): 512–20. Bibcode :1993Natur.365..512K . doi :10.1038/365512a0 . PMID 8413604 . S2CID 4336203 .
Vinson, C.; Sigler, P.; McKnight, S. (1989). "Scissors-grip model for DNA recognition by a family of leucine zipper proteins". Science . 246 (4932): 911–6. Bibcode :1989Sci...246..911V . doi :10.1126/science.2683088 . PMID 2683088 .
Otwinowski, Z; Schevitz, R. W.; Zhang, R. G.; Lawson, C. L.; Joachimiak, A; Marmorstein, R. Q.; Luisi, B. F.; Sigler, P. B. (1988). "Crystal structure of trp repressor /operator complex at atomic resolution". Nature . 335 (6188): 321–9. Bibcode :1988Natur.335..321O . doi :10.1038/335321a0 . PMID 3419502 . S2CID 9358980 .
See also [ edit ]
References [ edit ]
^ a b c d "Yale University Press Release" . 23 October 1998.
^ "Paul B. Sigler, MD, PhD - HHMI.org" . HHMI.org .
^ a b c "Paul Sigler (1934-2000) MRC Laboratory of Molecular Biology" .
^ a b "Blow on AcademicTree.org" .
^ National Academy of Sciences
^ "Official Site" .
^ Paul Sigler Memorial
^ "Paul Sigler Symposium" .
^ "Helen Hay Whitney Foundation - Announcement" .
Further reading [ edit ]
External links [ edit ]
R e t r i e v e d f r o m " https://en.wikipedia.org/w/index.php?title=Paul_Sigler&oldid=1184198787 " C a t e g o r i e s : ● P r i n c e t o n U n i v e r s i t y a l u m n i ● A m e r i c a n b i o p h y s i c i s t s ● 2 0 t h - c e n t u r y A m e r i c a n b i o c h e m i s t s ● Y a l e U n i v e r s i t y f a c u l t y ● U n i v e r s i t y o f C h i c a g o f a c u l t y ● Y a l e D e p a r t m e n t o f M o l e c u l a r B i o p h y s i c s & B i o c h e m i s t r y f a c u l t y ● S c i e n t i s t s f r o m N e w H a v e n , C o n n e c t i c u t ● S c i e n t i s t s f r o m C h i c a g o ● S c i e n t i s t s f r o m N e w Y o r k C i t y ● S c i e n t i s t s f r o m C a m b r i d g e ● S c i e n t i s t s f r o m P r i n c e t o n , N e w J e r s e y ● S c i e n t i s t s f r o m W a s h i n g t o n , D . C . ● P e o p l e f r o m R i c h m o n d , V i r g i n i a ● M e m b e r s o f t h e U n i t e d S t a t e s N a t i o n a l A c a d e m y o f S c i e n c e s ● H o w a r d H u g h e s M e d i c a l I n v e s t i g a t o r s ● 1 9 3 4 b i r t h s ● 2 0 0 0 d e a t h s ● C o l u m b i a U n i v e r s i t y V a g e l o s C o l l e g e o f P h y s i c i a n s a n d S u r g e o n s a l u m n i ● A l u m n i o f t h e U n i v e r s i t y o f C a m b r i d g e ● P h y s i c i a n s f r o m N e w H a v e n , C o n n e c t i c u t ● S c i e n t i s t s f r o m V i r g i n i a H i d d e n c a t e g o r i e s : ● A r t i c l e s w i t h s h o r t d e s c r i p t i o n ● S h o r t d e s c r i p t i o n m a t c h e s W i k i d a t a ● A r t i c l e s w i t h h C a r d s ● A l l a r t i c l e s w i t h u n s o u r c e d s t a t e m e n t s ● A r t i c l e s w i t h u n s o u r c e d s t a t e m e n t s f r o m M a y 2 0 2 3 ● A r t i c l e s w i t h I S N I i d e n t i f i e r s ● A r t i c l e s w i t h V I A F i d e n t i f i e r s ● A r t i c l e s w i t h W o r l d C a t E n t i t i e s i d e n t i f i e r s ● A r t i c l e s w i t h J 9 U i d e n t i f i e r s ● A r t i c l e s w i t h L C C N i d e n t i f i e r s
● T h i s p a g e w a s l a s t e d i t e d o n 8 N o v e m b e r 2 0 2 3 , a t 2 3 : 2 0 ( U T C ) . ● T e x t i s a v a i l a b l e u n d e r t h e C r e a t i v e C o m m o n s A t t r i b u t i o n - S h a r e A l i k e L i c e n s e 4 . 0 ;
a d d i t i o n a l t e r m s m a y a p p l y . B y u s i n g t h i s s i t e , y o u a g r e e t o t h e T e r m s o f U s e a n d P r i v a c y P o l i c y . W i k i p e d i a ® i s a r e g i s t e r e d t r a d e m a r k o f t h e W i k i m e d i a F o u n d a t i o n , I n c . , a n o n - p r o f i t o r g a n i z a t i o n . ● P r i v a c y p o l i c y ● A b o u t W i k i p e d i a ● D i s c l a i m e r s ● C o n t a c t W i k i p e d i a ● C o d e o f C o n d u c t ● D e v e l o p e r s ● S t a t i s t i c s ● C o o k i e s t a t e m e n t ● M o b i l e v i e w
