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F r o m W i k i p e d i a , t h e f r e e e n c y c l o p e d i a
Paula Veronica Welander is a microbiologist and professor at Stanford University [1] who is known for her research using lipid biomarkers to investigate how life evolved on Earth.
Early life and career [ edit ]
Welander was born and raised in the San Fernando Valley. Her mother and father immigrated from Mexico to Los Angeles in the early 1970’s.[2] She received her undergraduate degree from Occidental College in Los Angeles in 1998.[3] She has a master's degree (2003) and a Ph.D. (2007) from the University of Illinois at Urbana-Champaign .[3] She went on to do postdoctoral studies at Massachusetts Institute of Technology in the Departments of Biology and of Earth, Atmospheric, and Planetary Sciences.[4] Welander began her position at Stanford University in 2013,[3] and was awarded tenure in 2019.[4]
Research [ edit ]
Welander's graduate research examined factors controlling the use of methane by a group of Archaea .[5] For her postdoctoral research, she examined the production of a group of chemical compounds known as hopanoids .[6] [7] Welander has examined lipids in acid-loving archaea and how changes in the lipids alter a cell's ability to grow.[8] [9] Her research has further expanded our understanding of the organisms that produce triterpenoid lipids in aquatic environments.[10] Her more recent research centers on lipids, known as glycerol dibiphytanyl glycerol tetraethers (GDGTs), that are found in archaeal cell walls.[11] [12] Collectively, her research on lipids can be used to characterize how microbial life on Earth has changed over time.[13]
Honors and awards [ edit ]
In 2018, Welander received the Geobiology and Geomicrobiology Division Award for Outstanding Research from the Geological Society of America .[14] She also received a CAREER award from the National Science Foundation.[3]
Selected publications [ edit ]
Sessions, Alex L.; Doughty, David M.; Welander, Paula V.; Summons, Roger E.; Newman, Dianne K. (2009-07-28). "The Continuing Puzzle of the Great Oxidation Event" . Current Biology . 19 (14 ): R567–R574. doi :10.1016/j.cub.2009.05.054 . ISSN 0960-9822 . PMID 19640495 . S2CID 7346329 .
Welander, Paula V.; Hunter, Ryan C.; Zhang, Lichun; Sessions, Alex L.; Summons, Roger E.; Newman, Dianne K. (2009). "Hopanoids Play a Role in Membrane Integrity and pH Homeostasis in Rhodopseudomonas palustris TIE-1" . Journal of Bacteriology . 191 (19 ): 6145–6156. doi :10.1128/JB.00460-09 . ISSN 0021-9193 . PMC 2747905 . PMID 19592593 .
Welander, Paula V.; Coleman, Maureen L.; Sessions, Alex L.; Summons, Roger E.; Newman, Dianne K. (2010-05-11). "Identification of a methylase required for 2-methylhopanoid production and implications for the interpretation of sedimentary hopanes" . Proceedings of the National Academy of Sciences . 107 (19 ): 8537–8542. Bibcode :2010PNAS..107.8537W . doi :10.1073/pnas.0912949107 . ISSN 0027-8424 . PMC 2889317 . PMID 20421508 .
Wei, Jeremy H.; Yin, Xinchi; Welander, Paula V. (2016). "Sterol Synthesis in Diverse Bacteria" . Frontiers in Microbiology . 7 : 990. doi :10.3389/fmicb.2016.00990 . ISSN 1664-302X . PMC 4919349 . PMID 27446030 .
Welander, Paula V.; Summons, Roger E. (2012-08-07). "Discovery, taxonomic distribution, and phenotypic characterization of a gene required for 3-methylhopanoid production" . Proceedings of the National Academy of Sciences . 109 (32 ): 12905–12910. Bibcode :2012PNAS..10912905W . doi :10.1073/pnas.1208255109 . ISSN 0027-8424 . PMC 3420191 . PMID 22826256 .
References [ edit ]
^ a b c d "Paula V. Welander's Profile | Stanford Profiles" . profiles.stanford.edu . Retrieved 2022-08-26 .
^ a b "Dr. Paula Welander - Geobiology & Geomicrobiology Division" . community.geosociety.org . Retrieved 2022-08-26 .
^ Welander, Paula V.; Metcalf, William W. (2005-07-26). "Loss of the mtr operon in Methanosarcina blocks growth on methanol, but not methanogenesis, and reveals an unknown methanogenic pathway" . Proceedings of the National Academy of Sciences . 102 (30 ): 10664–10669. Bibcode :2005PNAS..10210664W . doi :10.1073/pnas.0502623102 . ISSN 0027-8424 . PMC 1180775 . PMID 16024727 .
^ Welander, Paula V.; Hunter, Ryan C.; Zhang, Lichun; Sessions, Alex L.; Summons, Roger E.; Newman, Dianne K. (2009). "Hopanoids Play a Role in Membrane Integrity and pH Homeostasis in Rhodopseudomonas palustris TIE-1" . Journal of Bacteriology . 191 (19 ): 6145–6156. doi :10.1128/JB.00460-09 . ISSN 0021-9193 . PMC 2747905 . PMID 19592593 .
^ Welander, Paula V.; Coleman, Maureen L.; Sessions, Alex L.; Summons, Roger E.; Newman, Dianne K. (2010-05-11). "Identification of a methylase required for 2-methylhopanoid production and implications for the interpretation of sedimentary hopanes" . Proceedings of the National Academy of Sciences . 107 (19 ): 8537–8542. Bibcode :2010PNAS..107.8537W . doi :10.1073/pnas.0912949107 . ISSN 0027-8424 . PMC 2889317 . PMID 20421508 .
^ Zeng, Zhirui; Liu, Xiao-Lei; Wei, Jeremy H.; Summons, Roger E.; Welander, Paula V. (2018-12-18). "Calditol-linked membrane lipids are required for acid tolerance in Sulfolobus acidocaldarius" . Proceedings of the National Academy of Sciences . 115 (51 ): 12932–12937. Bibcode :2018PNAS..11512932Z . doi :10.1073/pnas.1814048115 . ISSN 0027-8424 . PMC 6305003 . PMID 30518563 .
^ Hadhazy, Adam (March 2019). "Invulnerability Cloak". Natural History; New York . Vol. 127, no. 3. p. 8 – via ProQuest .
^ Banta, Amy B.; Wei, Jeremy H.; Gill, Clare C. C.; Giner, José-Luis; Welander, Paula V. (2017-01-10). "Synthesis of arborane triterpenols by a bacterial oxidosqualene cyclase" . Proceedings of the National Academy of Sciences . 114 (2 ): 245–250. Bibcode :2017PNAS..114..245B . doi :10.1073/pnas.1617231114 . ISSN 0027-8424 . PMC 5240688 . PMID 28028245 .
^ Zeng, Zhirui; Chen, Huahui; Yang, Huan; Chen, Yufei; Yang, Wei; Feng, Xi; Pei, Hongye; Welander, Paula V. (2022-03-22). "Identification of a protein responsible for the synthesis of archaeal membrane-spanning GDGT lipids" . Nature Communications . 13 (1 ): 1545. Bibcode :2022NatCo..13.1545Z . doi :10.1038/s41467-022-29264-x . ISSN 2041-1723 . PMC 8941075 . PMID 35318330 .
^ Zeng, Zhirui; Liu, Xiao-Lei; Farley, Kristen R.; Wei, Jeremy H.; Metcalf, William W.; Summons, Roger E.; Welander, Paula V. (2019-11-05). "GDGT cyclization proteins identify the dominant archaeal sources of tetraether lipids in the ocean" . Proceedings of the National Academy of Sciences . 116 (45 ): 22505–22511. Bibcode :2019PNAS..11622505Z . doi :10.1073/pnas.1909306116 . ISSN 0027-8424 . PMC 6842593 . PMID 31591189 .
^ Summons, Roger E.; Welander, Paula V.; Gold, David A. (2022). "Lipid biomarkers: molecular tools for illuminating the history of microbial life" . Nature Reviews Microbiology . 20 (3 ): 174–185. doi :10.1038/s41579-021-00636-2 . ISSN 1740-1526 . PMID 34635851 . S2CID 238637754 .
^ "Excellence Awards - Geobiology & Geomicrobiology Division" . community.geosociety.org . Retrieved 2022-08-26 .
External links [ edit ]
International
National
Academics
R e t r i e v e d f r o m " https://en.wikipedia.org/w/index.php?title=Paula_V._Welander&oldid=1226321187 "
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