RSU1 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Aliases | RSU1, RSP-1, Ras suppressor protein 1 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 179555; MGI: 103040; HomoloGene: 7521; GeneCards: RSU1; OMA:RSU1 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Ras suppressor protein 1 is a protein that in humans is encoded by the RSU1 gene.[5][6]
This gene encodes a protein that is involved in the Ras signal transduction pathway, growth inhibition, and nerve-growth factor induced differentiation processes, as determined in mouse and human cell line studies. In mouse, the encoded protein was initially isolated based on its ability to inhibit v-Ras transformation. Multiple alternatively spliced transcript variants for this gene have been reported; one of these variants was found only in glioma tumors.[6] RSU-1 has also been seen to act as a structural protein in integrin-mediated focal-adhesion complexes. It bind strongly to the protein PINCH.
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