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1 References  













Racivir






●فارسی
 ●Српски / srpski
 ●Srpskohrvatski / српскохрватски
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From Wikipedia, the free encyclopedia
  

Racivir

Clinical data

Routes of
administration

Investigational

ATC code

  • none

Identifiers

  • 4-amino-5-fluoro-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-1,2-dihydropyrimidin-2-one

CAS Number

PubChem CID

ChemSpider

UNII

NIAID ChemDB

CompTox Dashboard (EPA)

Chemical and physical data

Formula

C8H10FN3O3S

Molar mass

247.24 g·mol−1

3D model (JSmol)

  • c1c(c(nc(=O)n1[C@H]2CS[C@H](O2)CO)N)F

  • InChI=1S/C8H10FN3O3S/c9-4-1-12(8(14)11-7(4)10)5-3-16-6(2-13)15-5/h1,5-6,13H,2-3H2,(H2,10,11,14)/t5-,6+/m1/s1

  • Key:XQSPYNMVSIKCOC-RITPCOANSA-N

    • Racivir is an experimental nucleoside reverse transcriptase inhibitor (NRTI), developed by Pharmasset for the treatment of HIV.[1] It is the enantiomerofemtricitabine, a widely used NRTI, meaning that the two compounds are mirror images of each other.

    Emtricitabine, the enantiomer of racivir and a widely used NRTI

    References[edit]

    1. ^ "Racivir". AIDSmeds.com. March 24, 2006. Archived from the original on 2014-01-02. Retrieved March 21, 2008.


    Stub icon

    This antiinfective drug article is a stub. You can help Wikipedia by expanding it.

  • t
  • e
    • Antiviral drugs: antiretroviral drugs used against HIV (primarily J05)

    Capsid inhibitors

    Entry/fusion inhibitors
    (Discovery and development)

  • CCR5 (Maraviroc (MVC)
  • Vicriviroc†, Cenicriviroc†, Leronlimab†)
  • CD4 (Ibalizumab (IBA), Semzuvolimab§)
  • gp120 (Fostemsavir (FTR))

    • Integrase inhibitors
    (Integrase strand transfer inhibitors (INSTI))

  • Cabotegravir (CAB)
  • Dolutegravir (DTG)#
  • Elvitegravir (EVG)
  • Raltegravir (RAL)#
  • BI 224436†
  • MK-2048†

    • Maturation inhibitors

  • BMS-955176§
  • Fipravirimat§

    • Protease Inhibitors (PI)
    (Discovery and development)

    1st generation

  • Fosamprenavir (FPV)
  • Indinavir (IDV)◊
  • Lopinavir (LPV)
  • Nelfinavir (NFV)◊
  • Ritonavir (RTV)#
  • Saquinavir (SQV)◊

    • 2nd generation

  • Darunavir (DRV)°#
  • Tipranavir (TPV)◊
  • TMC-310911§

    • Reverse-transcriptase
    inhibitors     (RTIs)

    Nucleoside and
    nucleotide (NRTI)

  • Didanosine (ddI)◊
  • Emtricitabine (FTC)
  • Lamivudine (3TC)#
  • Stavudine (d4T)◊
  • Zalcitabine (ddC)‡
  • Zidovudine (AZT, ZDV)#
  • Amdoxovir†
  • Apricitabine†
  • Censavudine†
  • Elvucitabine†
  • Islatravir (EFdA, ISL)§
  • Racivir†
  • Stampidine†

    • Non-nucleoside (NNRTI)
    (Discovery and development)

    1st generation

  • Nevirapine (NVP)#
  • Delavirdine (DLV)‡

    • 2nd generation

  • Etravirine (ETR)
  • Rilpivirine (RPV)
  • Doravirine (DOR)
  • Elsulfavirine (ESV)

    • Combined formulations

  • Abacavir/dolutegravir/lamivudine°
  • Abacavir/lamivudine/zidovudine
  • Atazanavir/cobicistat
  • Bictegravir/emtricitabine/tenofovir alafenamide°
  • Cabotegravir/rilpivirine
  • Darunavir/cobicistat
  • Darunavir/cobicistat/emtricitabine/tenofovir alafenamide°
  • Dolutegravir/emtricitabine/tenofovir alafenamide
  • Dolutegravir/lamivudine°
  • Dolutegravir/lamivudine/tenofovir alafenamide°
  • Dolutegravir/lamivudine/tenofovir disoproxil°#
  • Dolutegravir/rilpivirine
  • Doravirine/lamivudine/tenofovir disoproxil
  • Efavirenz/emtricitabine/tenofovir disoproxil#
  • Efavirenz/lamivudine/tenofovir disoproxil#
  • Elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide
  • Elvitegravir/cobicistat/emtricitabine/tenofovir disoproxil
  • Emtricitabine/tenofovir alafenamide
  • Emtricitabine/rilpivirine/tenofovir alafenamide
  • Emtricitabine/rilpivirine/tenofovir disoproxil
  • Emtricitabine/tenofovir disoproxil#
  • Lamivudine/nevirapine/stavudine
  • Lamivudine/nevirapine/zidovudine
  • Lamivudine/raltegravir
  • Lamivudine/tenofovir disoproxil#
  • Lamivudine/zidovudine#
  • Lopinavir/ritonavir#

    • Pharmacokinetic boosters

  • Ritonavir (r)#

    • Experimental agents

    Uncoating inhibitors

    Transcription inhibitors

    Translation inhibitors

    BNAbs

    Other

  • BIT225†
  • Calanolide A
  • Ceragenin
  • Cyanovirin-N
  • Diarylpyrimidines
  • Epigallocatechin gallate (EGCG)
  • Foscarnet
  • Fosdevirine†
  • Griffithsin
  • Hydroxycarbamide
  • KP-1461†
  • Miltefosine
  • Portmanteau inhibitors
  • Scytovirin
  • Seliciclib†
  • Synergistic enhancers
  • Tre recombinase
  • Zinc finger protein transcription factor

    • Failed agents

  • Atevirdine
  • Brecanavir
  • Capravirine
  • Dexelvucitabine
  • Droxinavir
  • Lasinavir
  • Emivirine
  • Lersivirine
  • Lodenosine
  • Loviride
  • Mozenavir
  • Palinavir
  • Telinavir

  • ‡Withdrawn from market
  • Clinical trials:
  • §Never to phase III
    • °DHHS recommended initial regimen options. ◊Formerly or rarely used agent.

    Retrieved from "https://en.wikipedia.org/w/index.php?title=Racivir&oldid=1187850606"
    Categories: 
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     ●Organofluorides
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     ●Hydroxymethyl compounds
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    ●This page was last edited on 1 December 2023, at 20:45 (UTC).
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