Asprin's first novel, The Cold Cash War, an expansion of an earlier short story of the same title, was published in 1977.
During the next few years, he created and edited (with his then-wife, Lynn Abbey) the Thieves' World[5] series of shared world anthologies, credited as the first project of its type. Many of the authors later produced novels and stories of the theme which were not included in the anthologies, beginning with Beyond SanctuarybyJanet Morris, the first "authorized" Thieves World novel, published in 1985. Janet Morris and Chris Morris later produced two more authorized Thieves' World novels and a series of related novels about their character Tempus and the Sacred Band of Stepsons.[6] A series of graphic novels followed during the mid-1980s, and several other authors, including Andrew J. Offutt and David Drake, published novels about their characters. In 2002, Lynn Abbey revived the series with the novel Sanctuary.
During 1978, Asprin began the "MythAdventures" series, chronicling the comic adventures of Skeeve and Aahz, with the book Another Fine Myth. Illustrated originally by Frank Kelly Freas, and later by Phil Foglio, the pun-rich books concern a "demon" magician who has lost his powers and his inexperienced human apprentice as they travel through a variety of worlds. Some of the early "Myth" novels were adapted later as comic books by Foglio and others. The Myth books have been published by three publishing companies over the years: Donning Starblaze, Meisha Merlin and, as of 2008, Wildside Press.
During the 1990s, Asprin's "Phule" novels concerned the humorous science-fiction exploits of a rag-tag "Space Legion" and its wealthy and iconoclastic commander, Willard Phule.
Due to a series of personal and financial problems, Asprin published little during the 1990s, although he had two books on The New York Times Best Seller list, which piqued the interest of fans and the Internal Revenue Service. He eventually negotiated an agreement with the IRS[7] that encouraged him to resume writing, and during the early 2000s he published several novels, mostly in collaboration with authors Peter Heck, Jody Lynn Nye, and Linda Evans. These novels included continuations of the series "Myth Adventures" and "Phule's Company" as well as works of new series.
One of Asprin's last projects was NO Quarter, originally co-authored with Eric Del Carlo, and later edited by Teresa Patterson. It is a dark fantasy/suspense/murder mystery novel set in the author's beloved New Orleans French Quarter. Although the novel's fantasy elements (voodoo and black magic, tarot readings and precognition, ghosts and mysticism) are secondary to the brutal murder that is the emphasis of the plot, it is set in the same milieu as Asprin's Griffen McCandles novels (Dragons series), Dragons Luck and Dragons Wild. The two protagonists of NO Quarter, Maestro and Bone, also appear as minor characters of the Dragons novels. Maestro, the mysterious professional pool player and fencing master in NO Quarter, is fictionalized but based recognizably on the author. NO Quarter was published November 2009 by DarkStar Books.
Asprin's ofttimes co-author, Jody Lynn Nye, has completed one further Griffen McCandles novel, Dragons Deal, and continued the Myth Adventures series. Dragons Deal was published by Ace in December 2010.
Asprin died on May 22, 2008, of heart failure at his home in New Orleans.[8][9] He was found lying on a sofa with a Terry Pratchett novel still open in his hands.[10] He was to have been the Guest of Honor at Marcon that weekend.[11]
