Contents

Long-chain fatty acid transport protein 1

Protein-coding gene in the species Homo sapiens

SLC27A1
Identifiers
Aliases	SLC27A1, ACSVL5, FATP, FATP1, FATP-1, solute carrier family 27 member 1
External IDs	OMIM: 600691; MGI: 1347098; HomoloGene: 8063; GeneCards: SLC27A1; OMA:SLC27A1 - orthologs
Gene location (Human) Chr. Chromosome 19 (human)[1] Band 19p13.11 Start 17,468,769 bp[1] End 17,506,168 bp[1]
Gene location (Mouse) Chr. Chromosome 8 (mouse)[2] Band 8|8 B3.3 Start 71,568,882 bp[2] End 71,587,302 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in apex of heart pancreatic ductal cell right hemisphere of cerebellum muscle of thigh left ovary sural nerve right ovary C1 segment right adrenal cortex myocardium of left ventricle Top expressed in neural layer of retina muscle of thigh superior frontal gyrus choroid plexus of fourth ventricle lip white adipose tissue primary visual cortex ventricular zone subcutaneous adipose tissue phalanx of third toe More reference expression data BioGPS n/a
Gene ontology Molecular function long-chain fatty acid-CoA ligase activity nucleotide binding protein homodimerization activity ligase activity catalytic activity very long-chain fatty acid-CoA ligase activity fatty acid transmembrane transporter activity long-chain fatty acid transporter activity protein binding Cellular component cytoplasm integral component of membrane membrane plasma membrane endoplasmic reticulum endomembrane system mitochondrion mitochondrial inner membrane cytosol integral component of plasma membrane Biological process phosphatidic acid biosynthetic process phosphatidylserine biosynthetic process lipid transport lipid metabolism medium-chain fatty acid transport phosphatidylglycerol biosynthetic process fatty acid transport phosphatidylethanolamine biosynthetic process adiponectin-activated signaling pathway fatty acid metabolic process positive regulation of protein serine/threonine kinase activity response to insulin negative regulation of phospholipid biosynthetic process positive regulation of heat generation cardiolipin biosynthetic process phosphatidylinositol biosynthetic process response to cold phosphatidylcholine biosynthetic process metabolism long-chain fatty acid metabolic process long-chain fatty acid transport regulation of lipid metabolic process transport positive regulation of triglyceride biosynthetic process long-chain fatty acid import into cell Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 376497 26457 Ensembl ENSG00000130304 ENSMUSG00000031808 UniProt Q6PCB7 Q60714 RefSeq (mRNA) NM_198580 NM_011977 NM_001357180 NM_001357181 NM_001357182 RefSeq (protein) NP_940982 NP_036107 NP_001344109 NP_001344110 NP_001344111 Location (UCSC) Chr 19: 17.47 – 17.51 Mb Chr 8: 71.57 – 71.59 Mb PubMed search [3] [4]
Wikidata
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Long-chain fatty acid transport protein 1 (FATP1) is a protein that in humans is encoded by the SLC27A1 gene.^[5][6]

Structure[edit]

The SLC27A1 gene is located on the 19th chromosome, with its specific location being 19p13.11. The gene contains 15 exons.^[6] SLC27A1 encodes a 71.1 kDa protein that is composed of 646 amino acids; 26 peptides have been observed through mass spectrometry data.^[7][8]

See also[edit]

• SLC27A1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
• Solute carrier family

References[edit]

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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