Contents

SLC41A1

Protein-coding gene in the species Homo sapiens

SLC41A1
Identifiers
Aliases	SLC41A1, MgtE, solute carrier family 41 member 1, NPHPL2
External IDs	OMIM: 610801; MGI: 2444823; HomoloGene: 14871; GeneCards: SLC41A1; OMA:SLC41A1 - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1q32.1 Start 205,789,094 bp[1] End 205,813,748 bp[1]
Gene location (Mouse) Chr. Chromosome 1 (mouse)[2] Band 1|1 E4 Start 131,755,231 bp[2] End 131,776,603 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in myocardium of left ventricle cardiac muscle tissue of right atrium apex of heart right ventricle right auricle tibialis anterior muscle body of tongue body of pancreas vena cava Skeletal muscle tissue of biceps brachii Top expressed in extraocular muscle digastric muscle saccule stria vascularis optic nerve soleus muscle thoracic diaphragm sternocleidomastoid muscle ciliary body plantaris muscle More reference expression data BioGPS n/a
Gene ontology Molecular function cation transmembrane transporter activity magnesium ion transmembrane transporter activity magnesium:sodium antiporter activity transmembrane transporter activity Cellular component integral component of membrane membrane plasma membrane basolateral plasma membrane protein-containing complex Biological process cation transport ion transport sodium ion transmembrane transport magnesium ion transmembrane transport cellular magnesium ion homeostasis magnesium ion transport cellular response to magnesium ion Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 254428 98396 Ensembl ENSG00000133065 ENSMUSG00000013275 UniProt Q8IVJ1 Q8BJA2 RefSeq (mRNA) NM_173854 NM_173865 RefSeq (protein) NP_776253 NP_776290 Location (UCSC) Chr 1: 205.79 – 205.81 Mb Chr 1: 131.76 – 131.78 Mb PubMed search [3] [4]
Wikidata
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SLC41A1 is a protein that in humans is encoded by the gene SLC41A1.^[5] It is homologous to the prokaryotic Mg++ transfer protein MgtE^[6]

Mutations in this gene have been associated to Nephronophthisis-like phenotypes.^[7]

References[edit]