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Suzanne Frances Scarlata is the Richard Whitcomb Professor at Worcester Polytechnic Institute . She is known for her work on how cells respond to hormones and neurotransmitters. She is an elected fellow of the American Association for the Advancement of Science .
Education and career
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Scarlata grew up in Philadelphia[1] and received a B.A. from Temple University in 1979. She went on to earn her Ph.D. from the University of Illinois, Urbana-Champaign .[2] After her Ph.D. she accepted a position at AT&T Bell Laboratories where she worked on methods for testing circuit boards. She then moved to New York City where she worked at Cornell University Medical College . In 1991 she moved to Stony Brook University where she remained for 24 years.[1] In 2016 she moved to Worcester Polytechnic Institute where, as of 2022, she is the Richard Whitcomb Professor of Chemistry and Biochemistry.[2] In 2016, Scarlata was elected president of the Biophysical Society .[1]
Research
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In her own words, Scarlata is "fascinated by the way that cells grow, move, or die depending on their environment".[3] Her early research examined the motion of fluorophores .[4] [5] She went on to examine histones under high pressure,[6] the compression of lipid membranes,[7] and the binding affinities of compounds within lipids.[8] Scarlata is also interested in the use of enzymes to alter materials used in building construction. In 2021, Scarlata was involved in a research project that used the enzyme carbonic anhydrase to fix cracks in concrete.[9] [10]
Selected publications
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Rebecchi, M. J.; Scarlata, S. (1 June 1998). "PLECKSTRIN HOMOLOGY DOMAINS: A Common Fold with Diverse Functions" . Annual Review of Biophysics and Biomolecular Structure . 27 (1 ): 503–528. doi :10.1146/annurev.biophys.27.1.503 . ISSN 1056-8700 . PMID 9646876 .
Garcia, Pilar; Gupta, Rakesh; Shah, Shefali; Morris, Andrew J.; Rudge, Simon A.; Scarlata, Suzanne; Petrova, Victoria; McLaughlin, Stuart; Rebecchi, Mario J. (December 1995). "The pleckstrin homology domain of phospholipase C-.delta.1 binds with high affinity to phosphatidylinositol 4,5-bisphosphate in bilayer membranes". Biochemistry . 34 (49 ): 16228–16234. doi :10.1021/bi00049a039 . PMID 8519781 .
Scarlata, Suzanne; Carter, Carol (11 July 2003). "Role of HIV-1 Gag domains in viral assembly" . Biochimica et Biophysica Acta (BBA) - Biomembranes . 1614 (1 ): 62–72. doi :10.1016/S0005-2736(03 )00163-9 . ISSN 0005-2736 . PMID 12873766 .
Runnels, L.W.; Scarlata, S.F. (October 1995). "Theory and application of fluorescence homotransfer to melittin oligomerization" . Biophysical Journal . 69 (4 ): 1569–1583. Bibcode :1995BpJ....69.1569R . doi :10.1016/s0006-3495(95 )80030-5 . ISSN 0006-3495 . PMC 1236388 . PMID 8534828 .
Awards and honors
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In 2020 Scarlatta was elected a fellow of the American Association for the Advancement of Science.[11]
References
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^ "Suzanne Scarlata, Chemistry & Biochemistry" . WPI . Retrieved 2022-01-08 .
^ Rholam, Mohamed; Scarlata, Suzanne; Weber, Gregorio (1984-12-18). "Frictional resistance to the local rotations of fluorophores in proteins" . Biochemistry . 23 (26 ): 6793–6796. doi :10.1021/bi00321a079 . ISSN 0006-2960 .
^ Scarlata, Suzanne; Rholam, Mohamed; Weber, Gregorio (1984-12-18). "Frictional resistance to local rotations of aromatic fluorophores in some small peptides" . Biochemistry . 23 (26 ): 6789–6792. doi :10.1021/bi00321a078 . ISSN 0006-2960 .
^ Scarlata, Suzanne Frances; Ropp, Traci; Royer, Catherine A. (1989-08-08). "Histone subunit interactions as investigated by high pressure" . Biochemistry . 28 (16 ): 6637–6641. doi :10.1021/bi00442a016 . ISSN 0006-2960 . PMID 2790018 .
^ Scarlata, S.F. (1991). "Compression of lipid membranes as observed at varying membrane positions" . Biophysical Journal . 60 (2 ): 334–340. Bibcode :1991BpJ....60..334S . doi :10.1016/s0006-3495(91 )82058-6 . ISSN 0006-3495 . PMC 1260069 . PMID 1912276 .
^ Runnels, Loren W.; Jenco, John; Morris, Andrew; Scarlata, Suzanne (1996-01-01). "Membrane Binding of Phospholipases C-β1 and C-β2 Is Independent of Phosphatidylinositol 4,5-Bisphosphate and the α and βγ Subunits of G Proteins" . Biochemistry . 35 (51 ): 16824–16832. doi :10.1021/bi961606w . ISSN 0006-2960 . PMID 8988021 .
^ Rosewitz, Jessica A.; Wang, Shuai; Scarlata, Suzanne F.; Rahbar, Nima (2021-06-01). "An enzymatic self-healing cementitious material" . Applied Materials Today . 23 : 101035. doi :10.1016/j.apmt.2021.101035 . ISSN 2352-9407 . S2CID 234837645 .
^ Guimapang, Katherine (June 21, 2021). "Researchers develop a feasible solution for self-healing concrete in the construction industry" . Archinect . Retrieved 2022-01-07 .
^ "AAAS Announces Leading Scientists Elected as 2020 Fellows | American Association for the Advancement of Science" . www.aaas.org . Retrieved 2022-01-07 .
External links
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R e t r i e v e d f r o m " https://en.wikipedia.org/w/index.php?title=Suzanne_Scarlata&oldid=1220775390 "
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