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Contents

   



(Top)
  


1 Pharmacology  




2 Legality  




3 See also  




4 References  













THJ-018






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From Wikipedia, the free encyclopedia
  

THJ-018
Legal status
Legal status
  • DE: Anlage II (Authorized trade only, not prescriptible)
  • UK: Class B
    • Identifiers

    • 1-Naphthalenyl(1-pentyl-1H-indazol-3-yl)-methanone

    CAS Number
    ChemSpider
    UNII
    CompTox Dashboard (EPA)
    Chemical and physical data
    FormulaC23H22N2O
    Molar mass342.442 g·mol−1
    3D model (JSmol)

    • O=C(C1=NN(CCCCC)C2=C1C=CC=C2)C3=C4C(C=CC=C4)=CC=C3

    • InChI=1S/C23H22N2O/c1-2-3-8-16-25-21-15-7-6-13-20(21)22(24-25)23(26)19-14-9-11-17-10-4-5-12-18(17)19/h4-7,9-15H,2-3,8,16H2,1H3

    • Key:VAKGBPSFDNTMDJ-UHFFFAOYSA-N

    THJ-018 (SGT-17) is a synthetic cannabinoid that is the indazole analogue of JWH-018 and has been sold online as a designer drug.[1][2]

    Pharmacology[edit]

    THJ-018 acts as a full agonist with a binding affinity of 5.84 nM at CB1 and 4.57 nM at CB2 cannabinoid receptors.[3]

    Legality[edit]

    THJ-018 is an Anlage II controlled drug in Germany.[4] It is also banned in Sweden.[5]

    See also[edit]

    References[edit]

    1. ^ "THJ-018". Cayman Chemical. Retrieved 9 July 2015.
  • ^ Diao X, Wohlfarth A, Pang S, Scheidweiler KB, Huestis MA (January 2016). "High-Resolution Mass Spectrometry for Characterizing the Metabolism of Synthetic Cannabinoid THJ-018 and Its 5-Fluoro Analog THJ-2201 after Incubation in Human Hepatocytes". Clinical Chemistry. 62 (1): 157–69. doi:10.1373/clinchem.2015.243535. PMID 26430074.
  • ^ Hess C, Schoeder CT, Pillaiyar T, Madea B, Müller CE (2016). "Pharmacological evaluation of synthetic cannabinoids identified as constituents of spice". Forensic Toxicology. 34 (2): 329–343. doi:10.1007/s11419-016-0320-2. PMC 4929166. PMID 27429655.
  • ^ "Gesetz über den Verkehr mit Betäubungsmitteln (Betäubungsmittelgesetz - BtMG) Anlage II (zu § 1 Abs. 1) (verkehrsfähige, aber nicht verschreibungsfähige Betäubungsmittel)" (in German). Retrieved 9 July 2015.
  • ^ "Cannabinoider föreslås bli klassade som hälsofarlig vara" (in Swedish). Folkhälsomyndigheten. Retrieved 9 July 2015.
    • Stub icon

    This cannabinoid related article is a stub. You can help Wikipedia by expanding it.

  • t
  • e

    • Retrieved from "https://en.wikipedia.org/w/index.php?title=THJ-018&oldid=1186609566"
    Categories: 
    ●Cannabinoids
     ●Designer drugs
     ●Naphthoylindazoles
     ●Cannabinoid stubs
     Hidden categories: 
    ●CS1 German-language sources (de)
     ●CS1 Swedish-language sources (sv)
     ●Articles with short description
     ●Short description matches Wikidata
     ●Articles without EBI source
     ●Chemical pages without DrugBank identifier
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