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I think it might be worthwhile to mention that myelin increases resistance *across the membrane* specifically, because when you talk about the resistance in an axon, it could be the axial resistance or the membrane resistance. —The preceding unsigned comment was added by 128.54.210.152 (talk) 03:26, 5 February 2007 (UTC).[reply]
Furthermore, for someone who doesn't fully understand biophysics, resistance is bad. So when you have a line like "The main consequence of a myelin layer (or sheath) is an increase in the speed...Myelin increases resistance across the cell membrane by a factor of 5,000 ", it seems like a contradiction. And even this is contradictory "The main consequence of a myelin layer (or sheath) is an increase in the speed...Along unmyelinated fibers, impulses move continuously as waves, but, in myelinated fibers, they hop". I alwyas imagined continuous waves to be faster than "hopping" waves. Paskari (talk) 16:46, 2 July 2008 (UTC)[reply]
perhaps there should be a section about myelination in non vertibrates? it is mentioned in the introduction, but this is a really interesting field as myelin was long held to be hallmark of higher order organisms,
this is a good review if anyone is interested
FENESTRATION NODES AND THE WIDE SUBMYELINIC SPACE FORM THE BASIS
FOR THE UNUSUALLY FAST IMPULSE CONDUCTION OF SHRIMP MYELINATED
AXONS
KE XU (KE HSU) ANDSUSUMU TERAKAWA
The Journal of Experimental Biology 202, 1979–1989 (1999)
It isn't there for the simple reason that nobody has yet written it. If you folks care so much, one of you should write it. None of us are getting paid for this stuff, so nobody is obligated. Looie496 (talk) 01:16, 21 March 2011 (UTC)[reply]
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Hi. I have an amplified musculoskeletal pain syndrome. This means that my nerves send pain signals in response to stimuli that shouldn’t warrant such a response. One of my doctors recently told me that research shows part of the process of pain amplification is the growth of excess myelin sheath to literally grease the nerve pathways that cause pain, making those pathways easier to trigger. I don’t want to take the time to research it extensively, but if one of you is looking for a project I think this information would be a worthy addition to this page. Let me know your thoughts. Science Is My Life (talk) 00:23, 10 February 2018 (UTC)[reply]
The lead is too long and too detailed, and needs to cover major items detailed in the body of the text. The body of the text ought to have the details - neurofilaments amongst others are not mentioned in the body.--Iztwoz (talk) 22:10, 26 July 2018 (UTC)[reply]
@Julia Edgar: I agree with Iztwoz. The lead is way too long. I made a first pass attempt to reduce the size of the lead by splitting out some of the material into subsections. But more work is need so that the lead summarizes the entire article. Boghog (talk) 09:47, 28 July 2018 (UTC)[reply]