Contents

Talk:Triiodothyronine

This article is rated B-class on Wikipedia's content assessment scale. It is of interest to the following WikiProjects:

Physiology Mid‑importance This article is within the scope of WikiProject Physiology, a collaborative effort to improve the coverage of Physiology on Wikipedia. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks.PhysiologyWikipedia:WikiProject PhysiologyTemplate:WikiProject PhysiologyPhysiology articles Mid This article has been rated as Mid-importance on the importance scale. This article has not yet been associated with a particular area. Chemicals Low‑importance This article is within the scope of WikiProject Chemicals, a daughter project of WikiProject Chemistry, which aims to improve Wikipedia's coverage of chemicals. To participate, help improve this article or visit the project page for details on the project.ChemicalsWikipedia:WikiProject ChemicalsTemplate:WikiProject Chemicalschemicals articles Low This article has been rated as Low-importance on the project's importance scale. Molecular Biology: MCB This article is within the scope of WikiProject Molecular Biology, a collaborative effort to improve the coverage of Molecular Biology on Wikipedia. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks.Molecular BiologyWikipedia:WikiProject Molecular BiologyTemplate:WikiProject Molecular BiologyMolecular Biology articles ??? This article has not yet received a rating on the importance scale. This article is supported by the Molecular and Cell Biology task force (assessed as High-importance). This article has been marked as needing immediate attention.

Oppose merge[edit]

Oppose merge. Most of the information should remain in the thyroid hormone article, but it is useful to have this article in cases where the forms need to be distinguished. --Arcadian 03:17, 10 February 2007 (UTC)[reply]

I'm very concerned about the production heading, I really don't think that that's right. It has a biochemistry explanation that could be right (but doesn't look right and I don't have a textbook w/ me) and I think that a physiology explanation would be far more useful. A basic walk-through of the steps involved would probably do the casual reader a lot more justice. A3camero (talk) 01:14, 11 April 2008 (UTC)[reply]

1) I- and Na+ symport, iodine secreted into colloid

2) Iodine added to thyroglobulin to make T3 and T4 in the colloid

3) Iodinated thyroglobulin is then taken back up by the cell

4) Enzymes chop the thyroglobulin into T3 and T4

5) T3 and T4 are excreted into plasma -> enter circulation

References to "reverse-T3" and "TriiodoLIOthyronine" would be much appreciated in this article. Also, if anyone knows whether standard T3 blood tests include reverse-T3 or not.

Geebee2K (talk) 02:50, 22 March 2011 (UTC)[reply]

The involvement of thyroid peroxidase in iodinating tyrosine explained on this page contradicts the mechanism on the thyroid peroxidase page. That page says that iodine released by TPO spontaneously binds to the tyrosine with no TPO intermediation.

173.25.54.191 (talk) 23:00, 6 March 2013 (UTC)[reply]

The Synthesis of T4 section here says that Type I Deiodinase is responsible for 80% of the conversion of T4 to T3, and leaves it at that.

But the Iodothyronine_deiodinase#Types article claims that Type I Deiodinase is also capable of converting T4 into Reverse T3.

What's the scoop here?

--Rogermw (talk) 23:26, 15 November 2013 (UTC)[reply]