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I changed it to this:
"The inactive X chromosome is silenced by it being packaged in such a way that it has a transcriptionally inactive structure called heterochromatin."
Blueawr (talk) 09:40, 22 August 2012 (UTC)[reply]
I removed the following from the article. I have never heard of this and the reference does not indicate that it is true. This article is the only source that pops up with a search of the internet.
This section quotes the cytological work of Takagi et al. (1975), but seems to ignore the 1979 paper by Harper & Monk which showed double dosage of X-chromosome transcription/translation products (HGPRT) when female embryos were compared to males in mice around the 8-cell stage. This concurs with the Okamoto paper quoted "Here, we show that although initially active, the paternal X chromosome undergoes imprinted inactivation from the cleavage stages" (my emphasis), so the process is a bit more complex than stated. I don't have access to the papers behind a paywall, so cant review the actual methodology and have been out of the field for a long time. Semudobia (talk) 12:14, 10 May 2020 (UTC)[reply]