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From Wikipedia, the free encyclopedia
 


Valentina Martinez Mafla/sandbox
Clinical data
Trade namesClaritin, Claratyne, Clarityn, others
AHFS/Drugs.comMonograph
MedlinePlusa697038
License data
Pregnancy
category
  • Routes of
    administration
    By mouth
    Drug classSecond-generation antihistamine
    ATC code
    Legal status
    Legal status
  • UK: General sales list (GSL, OTC) / Pharmacy[3]
  • US: OTC / Rx-only
  • Pharmacokinetic data
    Bioavailabilityalmost 100%
    Protein binding97–99%
    Metabolismliver (CYP2D6- and 3A4-mediated)
    Elimination half-life8 hours, active metabolite desloratadine 27 hours
    Excretion40% as conjugated metabolites into urine
    Similar amount into the feces
    Identifiers
    • Ethyl 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylate

    CAS Number
    PubChem CID
    IUPHAR/BPS
    DrugBank
    ChemSpider
    UNII
    KEGG
    ChEBI
    ChEMBL
    Chemical and physical data
    FormulaC22H23ClN2O2
    Molar mass382.89 g·mol−1
    3D model (JSmol)
    • O=C(OCC)N4CC/C(=C2/c1ccc(Cl)cc1CCc3cccnc23)CC4

    • InChI=1S/C22H23ClN2O2/c1-2-27-22(26)25-12-9-15(10-13-25)20-19-8-7-18(23)14-17(19)6-5-16-4-3-11-24-21(16)20/h3-4,7-8,11,14H,2,5-6,9-10,12-13H2,1H3 checkY

    • Key:JCCNYMKQOSZNPW-UHFFFAOYSA-N checkY

     ☒NcheckY (what is this?)  (verify)
    1. ^ "Loratadine Use During Pregnancy". Drugs.com. 10 February 2020. Retrieved 10 April 2020.
  • ^ "Claritin Allergy Product information". Health Canada. 25 April 2012. Retrieved 7 June 2022.
  • ^ "Clarityn Allergy 10mg Tablets (P & GSL) - Patient Information Leaflet (PIL)". (emc). 30 August 2019. Archived from the original on 10 April 2020. Retrieved 10 April 2020.

  • Retrieved from "https://en.wikipedia.org/w/index.php?title=User:Valentina_Martinez_Mafla/sandbox&oldid=1149654886"





    This page was last edited on 13 April 2023, at 15:52 (UTC).

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