Contents

VSIG1

Protein-coding gene in the species Homo sapiens

VSIG1
Identifiers
Aliases	VSIG1, 1700062D20Rik, GPA34, dJ889N15.1, V-set and immunoglobulin domain containing 1
External IDs	OMIM: 300620; MGI: 1926039; HomoloGene: 12703; GeneCards: VSIG1; OMA:VSIG1 - orthologs
Gene location (Human) Chr. X chromosome (human)[1] Band Xq22.3 Start 108,044,970 bp[1] End 108,079,184 bp[1]
Gene location (Mouse) Chr. X chromosome (mouse)[2] Band X|X F1 Start 139,808,357 bp[2] End 139,840,221 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in pylorus right testis left testis pancreatic epithelial cell body of stomach cardia pancreatic ductal cell gallbladder gastric mucosa fundus Top expressed in testicle stomach spermatid spermatocyte duodenum islet of Langerhans colon right kidney quadriceps femoris muscle More reference expression data BioGPS n/a
Orthologs Species Human Mouse Entrez 340547 78789 Ensembl ENSG00000101842 ENSMUSG00000031430 UniProt Q86XK7 Q9D2J4 RefSeq (mRNA) NM_001170553 NM_182607 NM_026103 NM_030181 NM_001359143 RefSeq (protein) NP_001164024 NP_872413 NP_080379 NP_084457 NP_001346072 Location (UCSC) Chr X: 108.04 – 108.08 Mb Chr X: 139.81 – 139.84 Mb PubMed search [3] [4]
Wikidata
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V-set and immunoglobulin domain containing 1 is a protein that in humans is encoded by the VSIG1 gene.^[5]

Function[edit]

This gene encodes a member of the junctional adhesion molecule (JAM) family. The encoded protein contains multiple glycosylation sites at the N-terminal region, and multiple phosphorylation sites and glutamic acid/proline (EP) repeats at the C-terminal region. The gene is expressed in a normal stomach and testis, as well as in gastric, esophageal, and ovarian cancers. Alternatively spliced transcript variants, encoding different isoforms, have been found for this gene. [provided by RefSeq, Dec 2009].

References[edit]

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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