Val Melaina is in the northern part of the city, inside the Grande Raccordo Anulare. The boroughs of Nuovo Salario and Prati Fiscali are located within this zone.
The territory of Val Melaina includes the major part of the urban zone4BVal Melaina, a little part of the urban zone 4ESerpentara and the southern part of the urban zone 4LAeroporto dell'Urbe.
Northward, the zona borders with Castel Giubileo (Z. II), from which is separated by the countryside, between the river Tiber and Via Pian di Scò, by Via Pian di Scò itself, then by Via Gaetano Martino, Via Giacomo Brodolini and Viadotto Antonio Segni.
To the east, Val Melaina borders with Casal Boccone (Z. IV), whose boundary is marked by the stretch of Via delle Vigne Nuove between Viadotto Antonio Segni and Via Monte Resegone. To the south-east, it borders with QuartiereMonte Sacro (Q. XVI), from which is separated by Via Monte Resegone, Via Monte Massico, Via di Valle Melaina, Piazzale Jonio and Via dei Prati Fiscali up to Ponte Salario.
Southward, Val Melaina shares a border with QuartiereParioli (Q. II), which is outlined by the stretch of the river Aniene, between Ponte Salario and the Tiber.
Westward, the zona borders with QuartiereTor di Quinto (Q. XVIII) and with ZonaGrottarossa (Z. LVI): the boundary is marked by the river Tiber.
Streets and squares of Val Melaina are chiefly named after Italian politicians and, particularly in the borough of Nuovo Salario, after towns in Tuscany. Odonyms of Val Melaina can be categorized as follows: