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1 References  





2 External links  














Valienamine






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From Wikipedia, the free encyclopedia
 


Valienamine
Chemical structure of valienamine
Names
Preferred IUPAC name

(1S,2S,4R,6S)-6-Amino-4-(hydroxymethyl)cyclohex-4-ene-1,2,3-triol

Identifiers

CAS Number

3D model (JSmol)

ChEMBL
ChemSpider

PubChem CID

CompTox Dashboard (EPA)

  • InChI=1S/C7H13NO4/c8-4-1-3(2-9)5(10)7(12)6(4)11/h1,4-7,9-12H,2,8H2/t4-,5+,6-,7-/m0/s1 checkY

    Key: XPHOBMULWMGEBA-VZFHVOOUSA-N checkY

  • InChI=1/C7H13NO4/c8-4-1-3(2-9)5(10)7(12)6(4)11/h1,4-7,9-12H,2,8H2/t4-,5+,6-,7-/m0/s1

    Key: XPHOBMULWMGEBA-VZFHVOOUBJ

  • O[C@@H]1\C(=C/[C@H](N)[C@H](O)[C@H]1O)CO

Properties

Chemical formula

C7H13NO4
Molar mass 175.184 g·mol−1

Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

☒N verify (what is checkY☒N ?)

Infobox references

Valienamine is a C-7 aminocyclitol found as a substructure of pseudooligosaccharides such as the antidiabetic drug acarbose[1] and the antibiotic validamycin. It can be found in Actinoplanes species.[2]

It is an intermediate formed by microbial degradation of validamycins.[3]

References[edit]

  1. ^ Laube, Heiner (March 2002). "Acarbose An Update of Its Therapeutic Use in Diabetes Treatment". Clinical Drug Investigation. 22 (3): 141–156. doi:10.2165/00044011-200222030-00001.
  • ^ Zhang CS, Stratmann A, Block O, et al. (June 2002). "Biosynthesis of the C(7)-cyclitol moiety of acarbose in Actinoplanes species SE50/110. 7-O-phosphorylation of the initial cyclitol precursor leads to proposal of a new biosynthetic pathway". J. Biol. Chem. 277 (25): 22853–62. doi:10.1074/jbc.M202375200. PMID 11937512.
  • ^ CID 193758 from PubChem
  • External links[edit]


  • t
  • e

  • Retrieved from "https://en.wikipedia.org/w/index.php?title=Valienamine&oldid=1060011222"

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    This page was last edited on 12 December 2021, at 23:51 (UTC).

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