This article does not cite any sources. Please help improve this articlebyadding citations to reliable sources. Unsourced material may be challenged and removed.
Find sources: "Vitamin K-dependent protein" – news · newspapers · books · scholar · JSTOR (May 2019) (Learn how and when to remove this message) |
AVitamin K-dependent protein (VKDP) is a protein that can bind calcium ions but only after being carboxylated at a certain glutamic residue. This carboxylation, said to activate the protein, is facilitated by some form of vitamin K1orvitamin K2. The relevant part of a vitamin K-dependent protein is a Gla domain, and such a protein is informally called a Gla protein. Some Gla proteins have "Gla" in their name, for example Matrix Gla protein, but many don't, such as osteocalcin.